Khabbaz R F, Darrow W W, Hartley T M, Witte J, Cohen J B, French J, Gill P S, Potterat J, Sikes R K, Reich R
Division of Viral Diseases, Centers for Disease Control, Atlanta, Ga 30333.
JAMA. 1990 Jan 5;263(1):60-4.
We tested 1305 female prostitutes from eight areas of the United States for antibodies to human T-cell lymphotropic virus type I/II. Overall, 6.7% were human T-cell lymphotropic virus type I/II seropositive (with antibodies to both gag and env gene products). The seroprevalence rates ranged from 0% in southern Nevada to 25.4% in Newark, NJ. Human T-cell lymphotropic virus type I/II seropositivity was independently associated with race (odds ratio, 4.68), intravenous drug use (odds ratio, 2.94), hepatitis B seropositivity (odds ratio, 2.87), recruitment in Newark (odds ratio, 2.34), and more years of sexual activity (odds ratio, 1.08 per year of sexual activity). Groups with high rates included blacks, Hispanics, and American Indians, and the rates in these groups were significantly higher than among whites and Asian Americans for women both with and without a history of intravenous drug use. Among intravenous drug users, the only other independent associations were more years of sexual activity and recruitment in Newark; and in non-intravenous drug users, hepatitis B seropositivity. These data show that human T-cell lymphotropic virus type I/II infection is present among female prostitutes in some areas of the United States. Further studies are needed to evaluate patterns of transmission and long-term health effects.
我们对来自美国八个地区的1305名女性性工作者进行了I/II型人类嗜T细胞病毒抗体检测。总体而言，6.7%的人I/II型人类嗜T细胞病毒血清学呈阳性（对gag和env基因产物均有抗体）。血清阳性率从内华达州南部的0%到新泽西州纽瓦克的25.4%不等。I/II型人类嗜T细胞病毒血清阳性与种族（比值比，4.68）、静脉吸毒（比值比，2.94）、乙肝血清阳性（比值比，2.87）、在纽瓦克招募（比值比，2.34）以及更多年的性活动（每年性活动的比值比，1.08）独立相关。高感染率群体包括黑人、西班牙裔和美洲印第安人，无论有无静脉吸毒史，这些群体中的女性感染率均显著高于白人和亚裔美国人。在静脉吸毒者中，唯一的其他独立关联因素是更多年的性活动和在纽瓦克招募；而在非静脉吸毒者中，是乙肝血清阳性。这些数据表明，在美国一些地区的女性性工作者中存在I/II型人类嗜T细胞病毒感染。需要进一步研究以评估传播模式和长期健康影响。
