一名有苯丙胺滥用史者的急性脱髓鞘病变
Acute demyelination in a person with amphetamine abuse.
作者信息
Weis Serge, Sachs Hans, Büttner Andreas
机构信息
Laboratory of Neuropathology, Department of Pathology and Neuropathology, State Neuropsychiatric Hospital Wagner-Jauregg, Wagner-Jauregg-Weg 15, 4020 Linz, Austria.
出版信息
Case Rep Pathol. 2011;2011:514613. doi: 10.1155/2011/514613. Epub 2011 Oct 18.
Abstract
We report the case of a 31-year-old woman, admitted to the hospital for chest pain, dying a few days later from septic multiorgan failure, and showing at autopsy foci of acute demyelination in the occipital lobe. Gas chromatography/mass spectrometry analysis revealed the presence of amphetamine in the demyelinated area, which might be considered as the pathogenic agent, since other causes for demyelination could be excluded. This case represents the first report showing a demyelinating process due to a street drug.
摘要
我们报告了一例31岁女性病例，该患者因胸痛入院，数日后死于感染性多器官功能衰竭，尸检显示枕叶有急性脱髓鞘病灶。气相色谱/质谱分析显示脱髓鞘区域存在苯丙胺，由于可以排除其他脱髓鞘原因，苯丙胺可被视为病原体。该病例是首例显示因街头毒品导致脱髓鞘过程的报告。
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