Mutant Mouse Regional Resource Center (MMRRC), The Jackson Laboratory, Bar Harbor, ME, USA.
Mamm Genome. 2012 Oct;23(9-10):559-71. doi: 10.1007/s00335-012-9420-4. Epub 2012 Sep 4.
Because the mouse is used so widely for biomedical research and the number of mouse models being generated is increasing rapidly, centralized repositories are essential if the valuable mouse strains and models that have been developed are to be securely preserved and fully exploited. Ensuring the ongoing availability of these mouse strains preserves the investment made in creating and characterizing them and creates a global resource of enormous value. The establishment of centralized mouse repositories around the world for distributing and archiving these resources has provided critical access to and preservation of these strains. This article describes the common and specialized activities provided by major mouse repositories around the world.
由于老鼠在生物医学研究中被广泛应用,并且正在快速生成越来越多的老鼠模型,因此如果要安全保存和充分利用已经开发的有价值的老鼠品系和模型,集中式存储库是必不可少的。确保这些老鼠品系的持续可用性可以保留在创建和描述它们方面的投资,并创建一个具有巨大价值的全球资源。在世界各地建立集中的老鼠存储库,用于分发和归档这些资源,为这些品系提供了关键的访问和保存途径。本文描述了世界各地主要老鼠存储库提供的常见和专业活动。