Elbaz Johann, Moshe Michal, Willner Itamar
The Institute of Chemistry, The Hebrew University of Jerusalem, Jerusalem, 91904, Israel.
Angew Chem Int Ed Engl. 2009;48(21):3834-7. doi: 10.1002/anie.200805819.
Open sesame: Aptamer-substrate complexes activate the coherent operation of two tweezers that act as a "SET-RESET" logic system. Each tweezer cycles between a fluorescent open state and a closed quenched state (Q = quencher, F = fluorophore) when triggered by adenosine monophosphate (AMP) and adenosine deaminase (AD).
适体 - 底物复合物激活了两个作为“置位 - 复位”逻辑系统的镊子的协同操作。当受到单磷酸腺苷（AMP）和腺苷脱氨酶（AD）触发时，每个镊子在荧光开放状态和封闭淬灭状态之间循环（Q = 淬灭剂，F = 荧光团）。
