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扁桃体切除术和腺样体部分切除术对腭裂患者阻塞性睡眠呼吸暂停的疗效。

The effectiveness of tonsillectomy and partial adenoidectomy on obstructive sleep apnea in cleft palate patients.

机构信息

Department of Otolaryngology, Faculty of Medicine, Cairo University, Egypt.

出版信息

Laryngoscope. 2012 Nov;122(11):2563-7. doi: 10.1002/lary.23507. Epub 2012 Sep 5.

DOI:10.1002/lary.23507
PMID:22952113
Abstract

OBJECTIVES/HYPOTHESIS: The most common cause of pediatric obstructive sleep apnea (OSA) is adenotonsillar hypertrophy (ATH). In cleft palate patients, however, the obstructive effects of ATH are more severe due to narrow airways. The aim of this study was to assess the effectiveness of tonsillectomy and/or partial adenoidectomy on OSA in cleft palate patients.

STUDY DESIGN

Case series.

METHODS

Tonsillectomy and/or partial adenoidectomy was performed in 17 repaired cleft palate patients with tonsillar and/or adenoid hypertrophy and OSA. Apnea/hypopnea (A/H) index and minimum O(2) saturation were measured before and after surgery. In addition, because these patients are vulnerable to speech impairment after pharyngeal surgery, auditory perceptual assessment (APA) and nasometric assessment of speech were performed.

RESULTS

The mean preoperative A/H index was 17.6 ± 3.9, and the mean preoperative minimum O(2) saturation was 88.7 ± 1.5%. Both parameters improved postoperatively, to 1.9 ± 2.3 and 93.7 ± 1.5% respectively, and the changes were significant (P < 0.001). In 12 cases (70.6%), A/H indexes were normalized following surgery. Associated comorbidities such as retrognathia and narrow pharyngeal airways may underlie incomplete recovery in some cases. There were no significant postoperative changes in APA and nasalance scores.

CONCLUSIONS

In most cases, tonsillectomy and/or partial adenoidectomy is an effective method for treatment of OSA in repaired cleft palate patients presenting with tonsillar and/or adenoid hypertrophy. However, some cases may need further procedures to relieve airway obstruction due to associated comorbidities.

摘要

目的/假设:小儿阻塞性睡眠呼吸暂停(OSA)最常见的原因是腺样体扁桃体肥大(ATH)。然而,在腭裂患者中,由于气道狭窄,ATH 的阻塞效应更为严重。本研究旨在评估扁桃体切除术和/或腺样体切除术对腭裂患者 OSA 的疗效。

研究设计

病例系列。

方法

对 17 例有扁桃体和/或腺样体肥大和 OSA 的腭裂修复患者行扁桃体切除术和/或腺样体切除术。在手术前后测量呼吸暂停/低通气(A/H)指数和最低 O(2)饱和度。此外,由于这些患者在咽手术后易发生语音障碍,还进行了听觉感知评估(APA)和鼻音计语音评估。

结果

术前 A/H 指数平均为 17.6±3.9,术前最低 O(2)饱和度平均为 88.7±1.5%。术后两个参数均有改善,分别为 1.9±2.3 和 93.7±1.5%,变化具有统计学意义(P<0.001)。12 例(70.6%)患者术后 A/H 指数正常化。一些病例可能存在下颌后缩和咽腔狭窄等相关合并症,导致不完全恢复。APA 和鼻音计评分在术后无明显变化。

结论

在大多数情况下,扁桃体切除术和/或腺样体切除术是治疗伴有扁桃体和/或腺样体肥大的腭裂修复患者 OSA 的有效方法。然而,一些病例可能需要进一步的手术以缓解因相关合并症引起的气道阻塞。

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