促红细胞生成素在新生儿中的神经保护作用。
Neuroprotective role of erythropoietin in neonates.
作者信息
Juul Sandra
机构信息
Department of Paediatrics, Neonatology Division, University of Washington, Seattle, Washington 98195-6320, USA.
出版信息
J Matern Fetal Neonatal Med. 2012 Oct;25 Suppl 4:105-7. doi: 10.3109/14767058.2012.715025.
PMID:22958035
Abstract
This review summarizes target populations of neonates for which erythropoietin (Epo) neuroprotective therapy might be of benefit, and the mechanisms by which Epo functions as a neuroprotective agent. Potential risks of Epo are reviewed. Finally, the progression of Epo neuroprotection from preclinical studies to translational studies is discussed.
摘要
本综述总结了促红细胞生成素（Epo）神经保护疗法可能有益的新生儿目标人群，以及Epo作为神经保护剂发挥作用的机制。还综述了Epo的潜在风险。最后，讨论了Epo神经保护从临床前研究到转化研究的进展。
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