Schermerhorn Alice C, D'Onofrio Brian M, Slutske Wendy S, Emery Robert E, Turkheimer Eric, Harden K Paige, Heath Andrew C, Martin Nicholas G
Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA.
Twin Res Hum Genet. 2012 Dec;15(6):700-13. doi: 10.1017/thg.2012.55. Epub 2012 Sep 10.
Previous studies have found that child attention-deficit/hyperactivity disorder (ADHD) is associated with more parental marital problems. However, the reasons for this association are unclear. The association might be due to genetic or environmental confounds that contribute to both marital problems and ADHD.
Data were drawn from the Australian Twin Registry, including 1,296 individual twins, their spouses, and offspring. We studied adult twins who were discordant for offspring ADHD.Using a discordant twin pairs design, we examined the extent to which genetic and environmental confounds,as well as measured parental and offspring characteristics, explain the ADHD-marital problems association.
Offspring ADHD predicted parental divorce and marital conflict. The associations were also robust when comparing differentially exposed identical twins to control for unmeasured genetic and environmental factors, when controlling for measured maternal and paternal psychopathology,when restricting the sample based on timing of parental divorce and ADHD onset, and when controlling for other forms of offspring psychopathology. Each of these controls rules out alternative explanations for the association.
The results of the current study converge with those of prior research in suggesting that factors directly associated with offspring ADHD increase parental marital problems.
先前的研究发现,儿童注意力缺陷多动障碍(ADHD)与更多的父母婚姻问题有关。然而,这种关联的原因尚不清楚。这种关联可能是由于导致婚姻问题和ADHD的遗传或环境混杂因素。
数据来自澳大利亚双胞胎登记处,包括1296名个体双胞胎、他们的配偶和后代。我们研究了后代患有ADHD的成年双胞胎。采用不一致双胞胎对设计,我们研究了遗传和环境混杂因素以及测量的父母和后代特征在多大程度上解释了ADHD与婚姻问题之间的关联。
后代ADHD可预测父母离婚和婚姻冲突。在比较暴露程度不同的同卵双胞胎以控制未测量的遗传和环境因素时、在控制测量的父母精神病理学特征时、在根据父母离婚和ADHD发病时间限制样本时以及在控制其他形式的后代精神病理学特征时,这种关联同样显著。这些控制措施中的每一项都排除了该关联的其他解释。
当前研究结果与先前研究结果一致,表明与后代ADHD直接相关的因素会增加父母的婚姻问题。