Dipartimento di Chimica, Università di Roma La Sapienza, Piazzale Aldo Moro, 500185 Roma, Italy.
Nat Prod Res. 2013 Mar;27(4-5):412-6. doi: 10.1080/14786419.2012.724066. Epub 2012 Sep 10.
The analysis of the polar fraction of Galeopsis angustifolia Ehrh. ex Hoffm. indicates that the main components are iridoids and flavonoids. Six compounds were identified: a new flavonoid, 3'-hydroxy-isoscutellarein 7-O-[6'″acetyl-β-D-glucopyranosyl-(1 → 2)-β-D-glucopyranoside]; three iridoid glucosides: harpagide, acetyl harpagide and for the first time in this species, 8-epi-loganin; two known acetylated flavonoid glycosides: 3'-hydroxy-4'-O-methylisoscutellarein 7-O-[6'″acetyl-β-D-allopyranosyl-(1 → 2)-6″-acetyl-β-D-glucopyranoside], 3'-hydroxy-4'-O-methylisoscutellarein 7-O-[6'″acetyl-β-D-allopyranosyl-(1 → 2)-β-D-glucopyranoside]. Both flavonoids and iridoids are present in high amount; respectively, 16.7% and 4.5% of the crude extract.
对宽叶山柳菊（Galeopsis angustifolia Ehrh. ex Hoffm.）的极性部位进行分析，表明其主要成分为环烯醚萜苷和黄酮类化合物。鉴定出 6 种化合物：一种新的黄酮类化合物，3′-羟基异松蓝素 7-O-[6'″乙酰基-β-D-吡喃葡萄糖基-(1 → 2)-β-D-吡喃葡萄糖苷]；三种裂环环烯醚萜苷：哈巴苷、乙酰哈巴苷，以及在该种植物中首次发现的 8-表-.loggerenin；两种已知的乙酰化黄酮苷：3′-羟基-4′-O-甲基异松蓝素 7-O-[6'″乙酰基-β-D-吡喃阿拉伯糖苷-(1 → 2)-6″-乙酰基-β-D-吡喃葡萄糖苷]、3′-羟基-4′-O-甲基异松蓝素 7-O-[6'″乙酰基-β-D-吡喃阿拉伯糖苷-(1 → 2)-β-D-吡喃葡萄糖苷]。黄酮类化合物和环烯醚萜苷的含量都很高，分别占粗提取物的 16.7%和 4.5%。
