从狭叶山香圆（Galeopsis angustifolia Ehrh. ex Hoffm.）中分离得到一个新的类黄酮和其他极性化合物。

A new flavonoid and other polar compounds from Galeopsis angustifolia Ehrh. ex Hoffm.

机构信息

Dipartimento di Chimica, Università di Roma La Sapienza, Piazzale Aldo Moro, 500185 Roma, Italy.

出版信息

Nat Prod Res. 2013 Mar;27(4-5):412-6. doi: 10.1080/14786419.2012.724066. Epub 2012 Sep 10.

DOI:10.1080/14786419.2012.724066

Abstract

The analysis of the polar fraction of Galeopsis angustifolia Ehrh. ex Hoffm. indicates that the main components are iridoids and flavonoids. Six compounds were identified: a new flavonoid, 3'-hydroxy-isoscutellarein 7-O-[6'″acetyl-β-D-glucopyranosyl-(1 → 2)-β-D-glucopyranoside]; three iridoid glucosides: harpagide, acetyl harpagide and for the first time in this species, 8-epi-loganin; two known acetylated flavonoid glycosides: 3'-hydroxy-4'-O-methylisoscutellarein 7-O-[6'″acetyl-β-D-allopyranosyl-(1 → 2)-6″-acetyl-β-D-glucopyranoside], 3'-hydroxy-4'-O-methylisoscutellarein 7-O-[6'″acetyl-β-D-allopyranosyl-(1 → 2)-β-D-glucopyranoside]. Both flavonoids and iridoids are present in high amount; respectively, 16.7% and 4.5% of the crude extract.

摘要

对宽叶山柳菊（Galeopsis angustifolia Ehrh. ex Hoffm.）的极性部位进行分析，表明其主要成分为环烯醚萜苷和黄酮类化合物。鉴定出 6 种化合物：一种新的黄酮类化合物，3′-羟基异松蓝素 7-O-[6'″乙酰基-β-D-吡喃葡萄糖基-(1 → 2)-β-D-吡喃葡萄糖苷]；三种裂环环烯醚萜苷：哈巴苷、乙酰哈巴苷，以及在该种植物中首次发现的 8-表-.loggerenin；两种已知的乙酰化黄酮苷：3′-羟基-4′-O-甲基异松蓝素 7-O-[6'″乙酰基-β-D-吡喃阿拉伯糖苷-(1 → 2)-6″-乙酰基-β-D-吡喃葡萄糖苷]、3′-羟基-4′-O-甲基异松蓝素 7-O-[6'″乙酰基-β-D-吡喃阿拉伯糖苷-(1 → 2)-β-D-吡喃葡萄糖苷]。黄酮类化合物和环烯醚萜苷的含量都很高，分别占粗提取物的 16.7%和 4.5%。