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Use of the stepped wedge design cannot be recommended: a critical appraisal and comparison with the classic cluster randomized controlled trial design.

作者信息

Kotz Daniel, Spigt Mark, Arts Ilja C W, Crutzen Rik, Viechtbauer Wolfgang

机构信息

Department of General Practice, CAPHRI School for Public Health and Primary Care, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.

出版信息

J Clin Epidemiol. 2012 Dec;65(12):1249-52. doi: 10.1016/j.jclinepi.2012.06.004. Epub 2012 Sep 8.

DOI:10.1016/j.jclinepi.2012.06.004
PMID:22964070
Abstract
摘要

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Use of the stepped wedge design cannot be recommended: a critical appraisal and comparison with the classic cluster randomized controlled trial design.不推荐使用阶梯楔形设计：一项批判性评估以及与经典整群随机对照试验设计的比较。
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Systematic review of stepped wedge cluster randomized trials shows that design is particularly used to evaluate interventions during routine implementation.系统评价阶梯式楔形群随机试验表明，该设计特别用于在常规实施过程中评估干预措施。
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Researchers should convince policy makers to perform a classic cluster randomized controlled trial instead of a stepped wedge design when an intervention is rolled out.在推出一项干预措施时，研究人员应说服政策制定者进行经典的整群随机对照试验，而不是阶梯式楔形设计。
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[Application of 'stepped-wedge design' methodology in randomized controlled trials].["阶梯楔形设计'方法在随机对照试验中的应用]
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