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Researchers should convince policy makers to perform a classic cluster randomized controlled trial instead of a stepped wedge design when an intervention is rolled out.

作者信息

Kotz Daniel, Spigt Mark, Arts Ilja C W, Crutzen Rik, Viechtbauer Wolfgang

机构信息

Department of General Practice, CAPHRI School for Public Health and Primary Care, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.

出版信息

J Clin Epidemiol. 2012 Dec;65(12):1255-6. doi: 10.1016/j.jclinepi.2012.06.016. Epub 2012 Sep 8.

DOI:10.1016/j.jclinepi.2012.06.016
PMID:22964069
Abstract
摘要

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1
Researchers should convince policy makers to perform a classic cluster randomized controlled trial instead of a stepped wedge design when an intervention is rolled out.在推出一项干预措施时，研究人员应说服政策制定者进行经典的整群随机对照试验，而不是阶梯式楔形设计。
J Clin Epidemiol. 2012 Dec;65(12):1255-6. doi: 10.1016/j.jclinepi.2012.06.016. Epub 2012 Sep 8.
2
Use of the stepped wedge design cannot be recommended: a critical appraisal and comparison with the classic cluster randomized controlled trial design.不推荐使用阶梯楔形设计：一项批判性评估以及与经典整群随机对照试验设计的比较。
J Clin Epidemiol. 2012 Dec;65(12):1249-52. doi: 10.1016/j.jclinepi.2012.06.004. Epub 2012 Sep 8.
3
Systematic review showed that stepped-wedge cluster randomized trials often did not reach their planned sample size.系统评价显示，阶梯式楔形簇随机试验往往无法达到其计划的样本量。
J Clin Epidemiol. 2019 Mar;107:89-100. doi: 10.1016/j.jclinepi.2018.11.013. Epub 2018 Nov 17.
4
Inadequacy of ethical conduct and reporting of stepped wedge cluster randomized trials: Results from a systematic review.阶梯楔形整群随机试验的伦理行为及报告存在不足：一项系统评价的结果
Clin Trials. 2017 Aug;14(4):333-341. doi: 10.1177/1740774517703057. Epub 2017 Apr 8.
5
Minimum number of clusters and comparison of analysis methods for cross sectional stepped wedge cluster randomised trials with binary outcomes: A simulation study.具有二元结局的横断面阶梯楔形整群随机试验的最小聚类数及分析方法比较：一项模拟研究
Trials. 2017 Mar 9;18(1):119. doi: 10.1186/s13063-017-1862-2.
6
Power calculation in stepped-wedge cluster randomized trial with reduced intervention sustainability effect.具有降低的干预可持续性效应的阶梯楔形整群随机试验中的功效计算
J Biopharm Stat. 2019;29(4):663-674. doi: 10.1080/10543406.2019.1633658. Epub 2019 Jul 18.
7
A practical Bayesian stepped wedge design for community-based cluster-randomized clinical trials: The British Columbia Telehealth Trial.一种用于基于社区的整群随机临床试验的实用贝叶斯阶梯楔形设计：不列颠哥伦比亚远程医疗试验
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8
The stepped wedge design does not inherently have more power than a cluster randomized controlled trial.阶梯楔形设计本质上并不比整群随机对照试验更具效力。
J Clin Epidemiol. 2013 Sep;66(9):1059-60. doi: 10.1016/j.jclinepi.2013.05.004.
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Strengths and weaknesses of a stepped wedge cluster randomized design: its application in a colorectal cancer follow-up study.优势和劣势的一个阶梯式楔形群随机设计：其在结直肠癌随访研究中的应用。
J Clin Epidemiol. 2014 Apr;67(4):454-61. doi: 10.1016/j.jclinepi.2013.10.018. Epub 2014 Jan 31.
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There are some circumstances where the stepped-wedge cluster randomized trial is preferable to the alternative: no randomized trial at all. Response to the commentary by Kotz and colleagues.在某些情况下，阶梯楔形整群随机试验比另一种选择（即根本不进行随机试验）更可取。对Kotz及其同事评论的回应。
J Clin Epidemiol. 2012 Dec;65(12):1253-4. doi: 10.1016/j.jclinepi.2012.06.003. Epub 2012 Sep 9.

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