Gentile Pietro, Di Pasquali Camilla, Bocchini Ilaria, Floris Micol, Eleonora Tati, Fiaschetti Valeria, Floris Roberto, Cervelli Valerio
University of Study "Tor Vergata," Rome, Italy.
Surg Innov. 2013 Aug;20(4):370-6. doi: 10.1177/1553350612458544. Epub 2012 Sep 10.
The purpose of this study was to review the authors' experience of fat grafting, evaluating the effects related to the use of fat grafting with platelet-rich plasma (PRP) in the improvement of fat volume in breast reconstruction and comparing the results with a control group (only centrifuged fat grafting).
A total of 50 patients aged between 19 and 60 years affected by breast soft-tissue defects were analyzed at the Plastic and Reconstructive Department of the University of Tor Vergata. They were treated with fat grafting + PRP. The control group (50 patients with breast soft-tissue defects) were treated with centrifuged fat grafting injection according to Coleman's procedure.
The patients treated with PRP added to the autologous fat grafts showed a 69% maintenance of the contour restoring and of 3-dimensional volume after 1 year, whereas the patients of the control group treated with centrifuged fat grafting showed a 39% maintenance.
PRP mixed with fat grafting leads to an improvement in maintaining breast volume in patients affected by breast soft-tissue defects.
本研究旨在回顾作者的脂肪移植经验，评估富含血小板血浆（PRP）辅助脂肪移植在改善乳房重建中脂肪体积方面的效果，并与对照组（仅离心脂肪移植）的结果进行比较。
对罗马第二大学整形与重建科收治的50例年龄在19至60岁之间的乳房软组织缺损患者进行分析。他们接受了脂肪移植+PRP治疗。对照组（50例乳房软组织缺损患者）按照科尔曼技术接受离心脂肪移植注射治疗。
接受自体脂肪移植并添加PRP治疗的患者在1年后有69%的轮廓恢复和三维体积维持率，而接受离心脂肪移植治疗的对照组患者的维持率为39%。
PRP与脂肪移植混合使用可改善乳房软组织缺损患者的乳房体积维持情况。
