Kuratani S, Tanaka S
Department of Anatomy, Medical College of Georgia, Augusta 30912-2000.
Am J Anat. 1990 Jan;187(1):65-80. doi: 10.1002/aja.1001870108.
Development of the trigeminal nerve branches was studied in stage -17 to -27 chick embryos stained with an antibody to neurofilament protein. The following findings were obtained. 1) Ectopic ganglia transiently appeared in the ectoderm of the supraorbital region and were considered as remnant ophthalmic-placode-derived ganglia. 2) Most of the cutaneous sensory branches of the maxillomandibular nerve arose from a loosely arborized mass of neurites, provisionally termed the maxillomandibular reticulum, in which the fibers intermingled in a seemingly random fashion. 3) The growth of the trigeminal branches was mainly correlated with the development of the facial processes; however, irregular communications between different groups of branches were observed, suggesting that topographical organization of the peripheral branches is not rigid in early stages. 4) From the ophthalmic nerve around stage 23, transient dorsal rami developed and were distributed in the mesenchymal space, the cavum epiptericum, and passed near the ectoderm. Their homology with the rr. tentorii in human anatomy is suggested.
利用抗神经丝蛋白抗体对17至27期鸡胚进行染色，研究三叉神经分支的发育。获得了以下研究结果。1）异位神经节短暂出现在眶上区域的外胚层中，被认为是源自眼板残余的神经节。2）上颌下颌神经的大多数皮肤感觉分支起源于一个神经突疏松分支的团块，暂称为上颌下颌神经网，其中纤维以看似随机的方式相互交织。3）三叉神经分支的生长主要与面部突起的发育相关；然而，观察到不同分支组之间存在不规则的连通，这表明早期外周分支的拓扑组织并不严格。4）在23期左右，眼神经出现了短暂的背支，分布在间充质间隙（翼上腔）中，并在外胚层附近通过。提示它们与人体解剖学中的小脑幕支具有同源性。
