Mbadugha Chigozie A, Onakoya Adeola O, Aribaba Olufisayo T, Akinsola Folashade B
Guinness Eye Centre, Department of Ophthalmology, Lagos University, Teaching Hospital, Lagos State, Nigeria.
Clin Ophthalmol. 2012;6:1411-9. doi: 10.2147/OPTH.S33592. Epub 2012 Sep 3.
To compare two vision-specific quality of life (QOL) instruments - the disease-specific 15-item Glaucoma Quality of Life questionnaire (GQL-15) and the nonglaucoma-specific 25-item National Eye Institute Visual Function Questionnaire (NEIVFQ25).
The QOL of 132 glaucoma patients being managed in Lagos University Teaching Hospital and an equal number of controls matched for age and sex was assessed using two vision-specific instruments: GQL-15 and the NEIVFQ25. The categorization of the severity of glaucoma into mild, moderate, and severe disease was determined using the degree of visual field loss. The Statistical Package for the Social Sciences (version 15; SPSS Inc, Chicago, IL) software program was used for analyzing the data obtained. Spearman's correlation coefficients were used to assess the correlation between the scores from the two questionnaires.
Patients had the greatest difficulty with activities affected by glare and dark adaptation in the GQL-15. Driving and general vision were the factors most affected in the NEIVFQ25. The Spearman rho values showed strong correlations (rho > 0.55) between the NEIVFQ25 and GQL-15 QOL scores for the total number of participants (rho: -0.75), total number of cases (rho: -0.83), and the mild (rho: -0.76), moderate (rho: -0.75), and severe (rho: -0.84) cases. There was a moderate correlation (rho: -0.38) for QOL scores of controls. Cronbach's alpha was 0.94 for the GQL-15 and 0.93 for the NEIVFQ25, showing high internal consistency for both questionnaires.
The GQL-15 and the NEIVFQ25 questionnaires showed high internal consistency, correlated strongly with each other, and were reliable in the assessment of glaucoma patients in this study.
比较两种视力特异性生活质量（QOL）评估工具——特定疾病的15项青光眼生活质量问卷（GQL - 15）和非青光眼特异性的25项国家眼科研究所视觉功能问卷（NEIVFQ25）。
使用两种视力特异性评估工具GQL - 15和NEIVFQ25，对在拉各斯大学教学医院接受治疗的132例青光眼患者以及年龄和性别匹配的同等数量对照组的生活质量进行评估。根据视野缺损程度将青光眼严重程度分为轻度、中度和重度。使用社会科学统计软件包（版本15；SPSS公司，伊利诺伊州芝加哥）对获得的数据进行分析。采用Spearman相关系数评估两份问卷得分之间的相关性。
在GQL - 15中，患者在受眩光和暗适应影响的活动方面困难最大。在NEIVFQ25中，驾驶和总体视力是受影响最大的因素。Spearman相关系数显示，NEIVFQ25与GQL - 15生活质量得分在所有参与者总数（rho： - 0.75）、病例总数（rho： - 0.83）以及轻度（rho： - 0.76）、中度（rho： - 0.75）和重度（rho： - 0.84）病例中均呈现强相关性（rho > 0.55）。对照组生活质量得分的相关性为中等（rho： - 0.38）。GQL - 15的Cronbach's alpha系数为0.94，NEIVFQ25的为0.93，表明两份问卷均具有较高的内部一致性。
GQL - 15和NEIVFQ25问卷具有较高的内部一致性，相互之间相关性强，在本研究中对青光眼患者的评估是可靠的。
