Levecq H, Hautefeuille M, Hoang C, Galian A, Hautefeuille P, Rambaud J C
Service de Gastroentérologie, Hôpital Saint-Lazare, Paris, France.
Cancer. 1990 Feb 15;65(4):1028-32. doi: 10.1002/1097-0142(19900215)65:4<1028::aid-cncr2820650431>3.0.co;2-y.
A 73-year-old heterosexual man developed a high-grade non-Hodgkin's lymphoma at the site of an ileostomy only 2 years after proctectomy for undetermined colitis not cured by previous colectomy. In fact, the early occurrence of this usually very late and rare complication of ileostomy was probably favored by the simultaneous presence of acquired immune deficiency syndrome (AIDS) due to repeated blood transfusions for refractory anemia with excess blasts. The intestinal location of the tumor, its high-grade malignancy and B-cell origin are all features of AIDS-related non-Hodgkin's lymphoma. This case report seems to be one of the rarely identified examples of the cooperation between general predisposing factors and local irritating agents at the origin of a malignant tumor.
一名73岁的异性恋男性在因既往结肠切除术未治愈的不明原因结肠炎行直肠切除术后仅2年，在回肠造口部位发生了高级别非霍奇金淋巴瘤。事实上，这种通常非常晚期且罕见的回肠造口并发症的早期发生，可能是由于因难治性贫血伴原始细胞增多反复输血而同时存在获得性免疫缺陷综合征（AIDS）所致。肿瘤的肠道部位、高级别恶性程度和B细胞起源均为AIDS相关非霍奇金淋巴瘤的特征。本病例报告似乎是恶性肿瘤起源时一般易感因素与局部刺激因素协同作用的罕见实例之一。
