Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, 211 Eonjuro, Dogok-Dong, Gangnam-Gu, Seoul 135-720, South Korea.
Eur Radiol. 2013 Mar;23(3):658-63. doi: 10.1007/s00330-012-2647-3. Epub 2012 Sep 14.
To determine whether colour overlay features can be quantified by the standard deviation (SD) of the elasticity measured in shear-wave elastography (SWE) and to evaluate the diagnostic performance for breast masses.
One hundred thirty-three breast lesions in 119 consecutive women who underwent SWE before US-guided core needle biopsy or surgical excision were analysed. SWE colour overlay features were assessed using two different colour overlay pattern classifications. Quantitative SD of the elasticity value was measured with the region of interest including the whole breast lesion.
For the four-colour overlay pattern, the area under the ROC curve (Az) was 0.947; with a cutoff point between pattern 2 and 3, sensitivity and specificity were 94.4 % and 81.4 %. According to the homogeneity of the elasticity, the Az was 0.887; with a cutoff point between reasonably homogeneous and heterogeneous, sensitivity and specificity were 86.1 % and 82.5 %. For the SD of the elasticity, the Az was 0.944; with a cutoff point of 12.1, sensitivity and specificity were 88.9 % and 89.7 %. The colour overlay features showed significant correlations with the quantitative SD of the elasticity (P < 0.001).
The colour overlay features and the SD of the elasticity in SWE showed excellent diagnostic performance and showed good correlations between them.
确定剪切波弹性成像（SWE）中弹性测量的标准差（SD）是否可以量化彩色叠加特征，并评估其对乳腺肿块的诊断性能。
对 119 例连续接受 SWE 检查并行 US 引导下粗针活检或手术切除的女性的 133 个乳腺病变进行分析。使用两种不同的彩色叠加模式分类评估 SWE 彩色叠加特征。使用包括整个乳腺病变的感兴趣区域测量弹性值的 SD。
对于四色叠加模式，ROC 曲线下面积（Az）为 0.947；在模式 2 和 3 之间的截断点，灵敏度和特异性分别为 94.4%和 81.4%。根据弹性的均匀性，Az 为 0.887；在相当均匀和不均匀之间的截断点，灵敏度和特异性分别为 86.1%和 82.5%。对于弹性的 SD，Az 为 0.944；在 12.1 的截断点，灵敏度和特异性分别为 88.9%和 89.7%。彩色叠加特征与弹性的定量 SD 具有显著相关性（P<0.001）。
SWE 中的彩色叠加特征和弹性的 SD 具有出色的诊断性能，且两者之间相关性良好。
