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巴西亚马逊地区生物燃料生产对儿童居民的 PM（2.5）风险评估。

Risk assessment of PM(2.5) to child residents in Brazilian Amazon region with biofuel production.

机构信息

Public Health and Environment Post-graduation, National School of Public Health at Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.

出版信息

Environ Health. 2012 Sep 14;11:64. doi: 10.1186/1476-069X-11-64.

DOI:10.1186/1476-069X-11-64
PMID:22978271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3465199/
Abstract

BACKGROUND

Exposure to fine fractions of particulate matter (PM(2.5)) is associated with increased hospital admissions and mortality for respiratory and cardiovascular disease in children and the elderly. This study aims to estimate the toxicological risk of PM(2.5) from biomass burning in children and adolescents between the age of 6 and 14 in Tangará da Serra, a municipality of Subequatorial Brazilian Amazon.

METHODS

Risk assessment methodology was applied to estimate the risk quotient in two scenarios of exposure according to local seasonality. The potential dose of PM(2.5) was estimated using the Monte Carlo simulation, stratifying the population by age, gender, asthma and Body Mass Index (BMI).

RESULTS

Male asthmatic children under the age of 8 at normal body rate had the highest risk quotient among the subgroups. The general potential average dose of PM(2.5) was 1.95 μg/kg.day (95% CI: 1.62 - 2.27) during the dry scenario and 0.32 μg/kg.day (95% CI: 0.29 - 0.34) in the rainy scenario. During the dry season, children and adolescents showed a toxicological risk to PM(2.5) of 2.07 μg/kg.day (95% CI: 1.85 - 2 .30).

CONCLUSIONS

Children and adolescents living in the Subequatorial Brazilian Amazon region were exposed to high levels of PM(2.5) resulting in toxicological risk for this multi-pollutant. The toxicological risk quotients of children in this region were comparable or higher to children living in metropolitan regions with PM(2.5) air pollution above the recommended limits to human health.

摘要

背景

细颗粒物（PM(2.5)）暴露与儿童和老年人的呼吸道和心血管疾病住院率和死亡率增加有关。本研究旨在评估巴西亚马逊亚热带地区坦加拉达塞拉市 6 至 14 岁儿童和青少年生物质燃烧 PM(2.5)的毒理学风险。

方法

应用风险评估方法，根据当地季节性，在两种暴露情景下估计风险商数。使用蒙特卡罗模拟估计 PM(2.5)的潜在剂量，按年龄、性别、哮喘和体重指数（BMI）对人群进行分层。

结果

在正常体重率下，年龄在 8 岁以下的男性哮喘儿童在亚组中具有最高的风险商数。在干燥情景下，PM(2.5)的总潜在平均剂量为 1.95μg/kg.day（95%CI：1.62-2.27），在雨季为 0.32μg/kg.day（95%CI：0.29-0.34）。在干燥季节，儿童和青少年对 PM(2.5)的毒理学风险为 2.07μg/kg.day（95%CI：1.85-2.30）。

结论

生活在巴西亚马逊亚热带地区的儿童和青少年暴露于高水平的 PM(2.5)，导致这种多污染物存在毒理学风险。该地区儿童的毒理学风险商数与生活在 PM(2.5)空气污染超过人类健康推荐限值的大都市地区的儿童相当或更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6904/3465199/476f16d3cae6/1476-069X-11-64-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6904/3465199/f3c834c17f9a/1476-069X-11-64-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6904/3465199/476f16d3cae6/1476-069X-11-64-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6904/3465199/f3c834c17f9a/1476-069X-11-64-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6904/3465199/476f16d3cae6/1476-069X-11-64-2.jpg

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本文引用的文献

1
The Amazon basin in transition.亚马逊流域的变迁。
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2
Break down boundaries in climate research.打破气候研究中的界限。
Nature. 2012 Jan 18;481(7381):239. doi: 10.1038/481239a.
3
Exposure assessment for estimation of the global burden of disease attributable to outdoor air pollution.室外空气污染导致疾病全球负担估计的暴露评估。
幼儿园室内空气质量有效管理策略：一氧化碳和细颗粒物浓度
Toxics. 2023 Nov 16;11(11):931. doi: 10.3390/toxics11110931.
4
Air pollution from forest burning as environmental risk for millions of inhabitants of the Brazilian Amazon: an exposure indicator for human health.森林燃烧导致的空气污染对巴西亚马逊数百万居民的环境构成威胁：人类健康的暴露指标。
Cad Saude Publica. 2023 Jul 28;39(6):e00131422. doi: 10.1590/0102-311XEN131422. eCollection 2023.
5
Exposure to particulate matter (PM2.5) and volatile organic compounds (VOCs), and self-reported health symptoms among fish smokers: A case study in the Western Region of Ghana.鱼类熏制工暴露于颗粒物（PM2.5）和挥发性有机化合物（VOCs）与自述健康症状之间的关系：来自加纳西部地区的一项案例研究。
PLoS One. 2023 Mar 24;18(3):e0283438. doi: 10.1371/journal.pone.0283438. eCollection 2023.
6
Health risk assessment of particulate matter 2.5 in an academic metallurgy workshop.学术冶金车间内 2.5 颗粒物的健康风险评估。
Indoor Air. 2022 Sep;32(9):e13111. doi: 10.1111/ina.13111.
7
Elemental Composition of PM and PM and Health Risks Assessment in the Industrial Districts of Chelyabinsk, South Ural Region, Russia.俄罗斯南乌拉尔地区车里雅宾斯克工业区 PM 和 PM 元素组成及健康风险评估
Int J Environ Res Public Health. 2021 Nov 24;18(23):12354. doi: 10.3390/ijerph182312354.
8
Environmental Pollution and the Developing Lung.环境污染与发育中的肺
Clin Pulm Med. 2015 Jul;22(4):177-184. doi: 10.1097/cpm.0000000000000095.
9
Identification of Toxicity Parameters Associated with Combustion Produced Soot Surface Chemistry and Particle Structure by in Vitro Assays.通过体外试验鉴定与燃烧产生的烟尘表面化学和颗粒结构相关的毒性参数。
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Front Bioeng Biotechnol. 2020 May 29;8:519. doi: 10.3389/fbioe.2020.00519. eCollection 2020.
Environ Sci Technol. 2012 Jan 17;46(2):652-60. doi: 10.1021/es2025752. Epub 2012 Jan 6.
4
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Cad Saude Publica. 2011 Sep;27(9):1678-98. doi: 10.1590/s0102-311x2011000900003.
5
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Environ Health Perspect. 2011 Jul;119(7):1017-22. doi: 10.1289/ehp.1002913. Epub 2011 Jan 26.
6
Air pollution ultrafine particles: toxicity beyond the lung.空气污染超细颗粒：肺外毒性。
Eur Rev Med Pharmacol Sci. 2010 Oct;14(10):809-21.
7
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Cad Saude Publica. 2010 Apr;26(4):747-61. doi: 10.1590/s0102-311x2010000400017.
8
Particulate matter air pollution and cardiovascular disease: An update to the scientific statement from the American Heart Association.颗粒物空气污染与心血管疾病：美国心脏协会科学声明的更新。
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9
Evaluating the relative environmental impact of countries.评估各国的相对环境影响。
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10
Traffic-related particulate matter and acute respiratory symptoms among New York City area adolescents.交通相关颗粒物与纽约地区青少年急性呼吸道症状的关系。
Environ Health Perspect. 2010 Sep;118(9):1338-43. doi: 10.1289/ehp.0901499. Epub 2010 May 7.