Department of Anatomy and Neurobiology, Virginia Commonwealth University Medical Campus, Richmond, VA, USA.
Neurotoxicology. 2012 Oct;33(5):972-84. doi: 10.1016/j.neuro.2012.08.014. Epub 2012 Sep 5.
Accumulating evidence suggests that outdoor air pollution may have a significant impact on central nervous system (CNS) health and disease. To address this issue, the National Institute of Environmental Health Sciences/National Institute of Health convened a panel of research scientists that was assigned the task of identifying research gaps and priority goals essential for advancing this growing field and addressing an emerging human health concern. Here, we review recent findings that have established the effects of inhaled air pollutants in the brain, explore the potential mechanisms driving these phenomena, and discuss the recommended research priorities/approaches that were identified by the panel.
越来越多的证据表明,室外空气污染可能对中枢神经系统(CNS)健康和疾病产生重大影响。为了解决这个问题,美国国家环境卫生科学研究所/美国国立卫生研究院召集了一个研究科学家小组,负责确定研究空白和优先目标,这些目标对于推进这一不断发展的领域和解决新出现的人类健康问题至关重要。在这里,我们回顾了最近的发现,这些发现确立了吸入空气污染物对大脑的影响,探讨了驱动这些现象的潜在机制,并讨论了小组确定的建议研究重点/方法。