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颗粒物空气污染及其对人类和动物的呼吸影响。

Particulate matter air pollution and respiratory impact on humans and animals.

机构信息

Department of Veterinary Medicine, University of Bari 'Aldo Moro', 70010, Valenzano, Bari, Italy.

出版信息

Environ Sci Pollut Res Int. 2018 Dec;25(34):33901-33910. doi: 10.1007/s11356-018-3344-9. Epub 2018 Oct 4.

Abstract

Air pollution is now fully acknowledged to be a public health problem and a social issue. Particulate matter (PM) concentration has been linked with several clinical manifestations of pulmonary and cardiovascular diseases and is associated with morbidity and mortality induced by respiratory diseases both in human and animals. Current research on airborne particle-induced health effects investigates the critical characteristics of particulate matter that determine their biological effects. Scientific evidence assessed that the size of the airborne particles and their surface area determine the potential to elicit inflammatory injury, oxidative damage, and other biological effects. Thus, the present review paper aims to summarize the current evidences and findings on the effect of air pollution on lung function in both humans and animals.

摘要

空气污染现在已被充分认定为公共卫生问题和社会问题。颗粒物(PM)浓度与多种肺部和心血管疾病的临床表现有关,并与人类和动物的呼吸道疾病发病率和死亡率有关。目前,有关空气传播颗粒引起的健康影响的研究调查了决定其生物效应的颗粒物的关键特征。科学证据评估表明,空气传播颗粒的大小及其表面积决定了引发炎症损伤、氧化损伤和其他生物效应的潜力。因此,本综述论文旨在总结当前有关空气污染对人类和动物肺部功能影响的证据和发现。

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