Department of Radiology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.
J Cardiovasc Comput Tomogr. 2012 Sep-Oct;6(5):318-24. doi: 10.1016/j.jcct.2012.02.009. Epub 2012 Aug 16.
Several methods have been developed to reduce the radiation dose in coronary computed tomography angiography (CTA).
The objective of our study was to evaluate the effects of Adaptive Iterative Dose Reduction (AIDR) on objective and subjective image quality as well as the radiation dose, compared with conventional filtered back projection (FBP), in coronary CTA.
We retrospectively reviewed 100 consecutive patients who underwent coronary CTA. In the first 50 patients, a higher tube current was used, and images were reconstructed with FBP. In the last 50 patients, a lower tube current was used, and images were reconstructed with AIDR. Subjective and objective image quality (noise, signal-to-noise ratio, contrast-to-noise ratio) were assessed.
The median radiation dose of the AIDR group was 22% lower than that of the FBP group (4.2 vs 5.4 mSv; P = 0.0001). No significant difference was found in subjective image quality, noise, signal-to-noise ratio, or contrast-to-noise ratio between the 2 groups.
AIDR reduced the tube current which resulted in reduction of radiation dose in coronary CTA while maintaining subjective and objective image quality compared with coronary CTA reconstructed with FBP.
已经开发出多种方法来降低冠状动脉 CT 血管造影(CTA)的辐射剂量。
本研究旨在评估与传统滤波反投影(FBP)相比,自适应迭代剂量降低(AIDR)对冠状动脉 CTA 的客观和主观图像质量以及辐射剂量的影响。
我们回顾性分析了 100 例连续接受冠状动脉 CTA 的患者。在前 50 例患者中,使用较高的管电流,并使用 FBP 重建图像。在后 50 例患者中,使用较低的管电流,并使用 AIDR 重建图像。评估了主观和客观图像质量(噪声、信噪比、对比噪声比)。
AIDR 组的辐射剂量中位数比 FBP 组低 22%(4.2 与 5.4 mSv;P = 0.0001)。两组之间的主观图像质量、噪声、信噪比或对比噪声比均无显著差异。
与 FBP 重建的冠状动脉 CTA 相比,AIDR 降低了管电流,从而降低了冠状动脉 CTA 的辐射剂量,同时保持了主观和客观的图像质量。