Ali Niloufer Sultan, Khuwaja Ali Khan, Nanji Kashmira
Department of Family Medicine, Aga Khan University Hospital, Aga Khan University, Stadium Road, P.O. Box 3500, Karachi 74800, Pakistan.
Int J Family Med. 2012;2012:649383. doi: 10.1155/2012/649383. Epub 2012 Sep 5.
Background. Metabolic Syndrome (MetS) is a major public health concern. Objective. The aim of this study was to estimate the frequency of MetS, its components, and factors associated with MetS amongst apparently healthy individuals in Pakistan. Methods. A retrospective cross-sectional study was conducted at the executive Clinics of Aga Khan Hospital, Pakistan. Medical records of patients aged ≥18 years visiting the clinics from July 2011 to December 2011 were consecutively reviewed. Records in which either MetS components data or 10% of overall data was missing were excluded. A total of 1329 participants' records was included in final analysis. Data was analyzed using SPSS version 19 and multivariable logistic regression was used to identify the factors associated with MetS. Results. A total of 847 (63.7%) participants had MetS; mean age of the participants were 47.6 ± 11.6 years. About 70.4% were males and 29.6% were females. Approximately 70% of participants had BMI ≥25 kg/m(2). MetS was associated with male gender (AOR = 2.1; 95% C.I: 1.6-3.2) and history of diabetes among parents (AOR = 3.0; 95% C.I: 1.6-6.0). Conclusion. This study shows that a large proportion of population has MetS and is overweight or obese. This requires urgent interventions on part of health care providers' especially family physicians. Educating masses about life style factors can make a difference. Further researches on this issue are warranted.
背景。代谢综合征（MetS）是一个主要的公共卫生问题。目的。本研究的目的是估计巴基斯坦看似健康的个体中代谢综合征及其组成成分的发生率以及与代谢综合征相关的因素。方法。在巴基斯坦阿迦汗医院的行政诊所进行了一项回顾性横断面研究。连续审查了2011年7月至2011年12月到诊所就诊的年龄≥18岁患者的病历。排除代谢综合征组成成分数据缺失或总体数据缺失10%的记录。最终分析纳入了1329名参与者的记录。使用SPSS 19版软件进行数据分析，并使用多变量逻辑回归来确定与代谢综合征相关的因素。结果。共有847名（63.7%）参与者患有代谢综合征；参与者的平均年龄为47.6±11.6岁。约70.4%为男性，29.6%为女性。大约70%的参与者BMI≥25 kg/m²。代谢综合征与男性性别（比值比[AOR]=2.1；95%置信区间[C.I]：1.6 - 3.2）以及父母有糖尿病病史（比值比[AOR]=3.0；95%置信区间[C.I]：1.6 - 6.0）相关。结论。本研究表明，很大一部分人群患有代谢综合征且超重或肥胖。这需要医疗保健提供者尤其是家庭医生进行紧急干预。对大众进行生活方式因素的教育可能会有所帮助。对此问题进行进一步研究是有必要的。
