Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.
Occup Environ Med. 2013 Aug;70(8):523-8. doi: 10.1136/oemed-2011-100017. Epub 2012 Sep 19.
Evidence from general population-based studies and occupational cohorts has identified air pollution from mobile sources as a risk factor for cardiovascular disease. In a cohort of US trucking industry workers, with regular exposure to vehicle exhaust, the authors previously observed elevated standardised mortality ratios for ischaemic heart disease (IHD) compared with members of the general US population. Therefore, the authors examined the association of increasing years of work in jobs with vehicle exhaust exposure and IHD mortality within the cohort.
The authors calculated years of work in eight job groups for 30,758 workers using work records from four nationwide companies. Proportional hazard regression was used to examine relationships between IHD mortality, 1985-2000, and employment duration in each job group.
HRs for at least 1 year of work in each job were elevated for dockworkers, long haul drivers, pick-up and delivery drivers, combination workers, hostlers, and shop workers. There was a suggestion of an increased risk of IHD mortality with increasing years of work as a long haul driver, pick-up and delivery driver, combination worker, and dockworker.
These results suggest an elevated risk of IHD mortality in workers with a previous history of regular exposure to vehicle exhaust.
来自一般人群研究和职业队列的证据表明,移动源空气污染是心血管疾病的一个风险因素。在一项针对美国卡车运输业工人的队列研究中,由于经常接触汽车尾气,作者先前观察到与美国一般人群相比,缺血性心脏病(IHD)的标准化死亡率升高。因此,作者在队列中检查了与接触车辆尾气的工作年限增加与 IHD 死亡率之间的关联。
作者使用来自四家全国性公司的工作记录,为 30758 名工人计算了在八个工作类别中的工作年限。使用比例风险回归来检验 IHD 死亡率(1985-2000 年)与每个工作类别的工作年限之间的关系。
在码头工人、长途司机、取送货司机、组合工人、调车员和车间工人中,每种工作至少工作 1 年的 HR 均升高。随着作为长途司机、取送货司机、组合工人和码头工人的工作年限的增加,IHD 死亡率的风险似乎增加。
这些结果表明,有既往规律接触汽车尾气史的工人患 IHD 死亡的风险升高。