Department of Psychology, University of California at Davis, 1544 Newton Ct., Davis, California 95618, USA.
Nat Rev Neurosci. 2012 Oct;13(10):713-26. doi: 10.1038/nrn3338.
Although the perirhinal cortex (PRC), parahippocampal cortex (PHC) and retrosplenial cortex (RSC) have an essential role in memory, the precise functions of these areas are poorly understood. Here, we review the anatomical and functional characteristics of these areas based on studies in humans, monkeys and rats. Our Review suggests that the PRC and PHC-RSC are core components of two separate large-scale cortical networks that are dissociable by neuroanatomy, susceptibility to disease and function. These networks not only support different types of memory but also appear to support different aspects of cognition.
虽然边缘脑回（PRC）、海马旁回皮质（PHC）和后穹窿皮质（RSC）在记忆中起着重要作用，但这些区域的确切功能仍不清楚。在这里，我们根据人类、猴子和老鼠的研究综述了这些区域的解剖学和功能特征。我们的综述表明，PRC 和 PHC-RSC 是两个独立的大规模皮质网络的核心组成部分，它们可以通过神经解剖学、疾病易感性和功能来区分。这些网络不仅支持不同类型的记忆，而且似乎还支持认知的不同方面。
