Department of Anesthesiology and Intensive Care, Örebro University Hospital, Örebro, Sweden.
Acta Anaesthesiol Scand. 2012 Nov;56(10):1306-13. doi: 10.1111/j.1399-6576.2012.02771.x. Epub 2012 Sep 24.
A common complaint after endotracheal intubation is sore throat and hoarseness. The aim of this study was to describe gender differences and independent risk factors in the development of post-operative sore throat and hoarseness after endotracheal intubation in adults.
This prospective cross-sectional observational study was conducted at a university hospital in Sweden. A total of 495 patients were included (203 men and 292 women) and enrolled from a total of eight different surgical departments. Outcome variables were post-operative sore throat and hoarseness evaluated post-operatively in the post-anaesthesia care unit. A total of 31 variables were recorded which described the intubation process, intraoperative factors as well as the extubation process. Bivariate and multivariate analyses were performed.
The overall incidence of post-operative sore throat was 35% and hoarseness 59%. The results show different predictors for men and women in the development of airway symptoms. The main risk factor for developing sore throat in men was intubation by personnel with < 3 months' work experience. In women, it was endotracheal tube size 7.0 and multiple laryngoscopies during intubation. The main risk factors for hoarseness were cuff pressure for both men and women, and oesophageal temperature probe in women.
Post-operative sore throat and hoarseness result from several factors, and the cause of these symptoms are multifactorial and differs by gender. Identification of these factors pre-operatively may increase awareness among anaesthesia personnel and possibly reduce the incidence of these minor but distressing symptoms.
气管插管后常见的主诉是咽喉痛和声嘶。本研究旨在描述成年患者气管插管后发生术后咽喉痛和声嘶的性别差异和独立危险因素。
这是一项在瑞典一所大学医院进行的前瞻性横断面观察性研究。共纳入 495 例患者（男 203 例，女 292 例），来自 8 个不同的外科科室。术后咽喉痛和声嘶是在麻醉后恢复室（PACU）进行评估的术后结局变量。共记录了 31 个变量，描述了插管过程、术中因素以及拔管过程。进行了单变量和多变量分析。
术后咽喉痛的总发生率为 35%，声嘶为 59%。结果表明，男女在气道症状发生发展方面有不同的预测因素。男性发生咽喉痛的主要危险因素是工作人员工作经验<3 个月的插管。对于女性，主要危险因素是气管导管大小为 7.0 以及插管时多次进行喉镜检查。咽喉痛的主要危险因素是男女的气囊压力，以及女性的食管温度探头。
术后咽喉痛和声嘶是由多种因素引起的，这些症状的原因是多因素的，且因性别而异。术前识别这些因素可能会提高麻醉人员的认识，并可能降低这些轻微但令人痛苦的症状的发生率。
