Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Am J Pathol. 2012 Nov;181(5):1513-7. doi: 10.1016/j.ajpath.2012.09.001. Epub 2012 Sep 20.
This Commentary highlights the article by Fang et al, which describes novel mouse models of chronic intermittent hypoxia (CIH)-induced atherosclerosis, revealing that loss of the NF-κB p50 subunit increased atherosclerosis in the presence of CIH.
本述评重点介绍了 Fang 等人的文章,该文章描述了慢性间歇性低氧(CIH)诱导动脉粥样硬化的新型小鼠模型,揭示了 NF-κB p50 亚基缺失会增加 CIH 状态下的动脉粥样硬化。