Department of Nutrition and Dietetics, Harokopio University, 70 El. Venizelou Street, 17671 Athens, Greece.
Public Health Nutr. 2013 Mar;16(3):479-86. doi: 10.1017/S1368980012002613. Epub 2012 Sep 25.
The present study aimed to evaluate the relationship between the consumption of selected food groups and insulin resistance, with an emphasis on sugar-sweetened beverages (SSB).
The present research is a large multicentre European study in adolescents, the HELENA-CSS (Healthy Lifestyle in Europe by Nutrition in Adolescence Cross-Sectional Study).
Homeostasis model assessment-insulin resistance index (HOMA-IR) was calculated. Several anthropometric and lifestyle characteristics were recorded. Dietary assessment was conducted by using a short FFQ.
The participants were a subset of the original sample (n 546) with complete data on glucose, insulin and FFQ. All participants were recruited at schools.
Median (25th, 75th percentile) HOMA-IR was 0.62 (0.44, 0.87). Mean HOMA-IR was significantly higher among adolescents consuming brown bread ≤1 time/week than among those consuming 2-6 times/week (P = 0·011). Mean values of HOMA-IR were also higher in adolescents consuming SSB >5 times/week compared with those consuming less frequently, although a statistically significant difference was detected between those consuming SSB 5-6 times/week and 2-4 times/week (P = 0.049). Multiple linear regression analysis showed that only the frequency of SSB consumption was significantly associated with HOMA-IR after controlling for potential confounders. In particular, it was found that HOMA-IR levels were higher among adolescents consuming SSB 5-6 times/week and ≥1 time/d compared with those consuming ≤1 time/week by 0.281 and 0.191 units, respectively (P = 0.009 and 0.046, respectively).
The present study revealed that daily consumption of SSB was related with increased HOMA-IR in adolescents.
本研究旨在评估特定食物组的消费与胰岛素抵抗之间的关系，重点关注含糖饮料（SSB）。
本研究是一项在青少年中进行的大型欧洲多中心研究，即 HELENA-CSS（青少年营养横断面研究中的欧洲健康生活方式）。
计算了稳态模型评估-胰岛素抵抗指数（HOMA-IR）。记录了几种人体测量和生活方式特征。通过使用简短的 FFQ 进行饮食评估。
具有完整血糖、胰岛素和 FFQ 数据的原始样本的一个子集（n 546）。所有参与者均在学校招募。
中位数（25 分位，75 分位）HOMA-IR 为 0.62（0.44，0.87）。每周食用 1 次以下的青少年的平均 HOMA-IR 明显高于每周食用 2-6 次的青少年（P = 0.011）。每周食用 SSB >5 次的青少年的 HOMA-IR 平均值也较高，尽管与每周食用 2-4 次的青少年相比，差异具有统计学意义（P = 0.049）。多元线性回归分析显示，在控制了潜在混杂因素后，只有 SSB 的消费频率与 HOMA-IR 显著相关。特别是，每周食用 SSB 5-6 次和≥1 次/d 的青少年的 HOMA-IR 水平分别比每周食用≤1 次的青少年高 0.281 和 0.191 单位（P = 0.009 和 0.046）。
本研究表明，青少年每天饮用 SSB 与 HOMA-IR 升高有关。
