Department of Experimental Biology, Anthropological Science Section, University of Cagliari, Cagliari, Italy.
Nutrition. 2013 Jan;29(1):132-7. doi: 10.1016/j.nut.2012.05.007. Epub 2012 Sep 23.
The aim of the present research was to show the characteristics of body composition in a sample of elderly subjects with type 2 diabetes compared with healthy controls matched by age and body mass index (BMI) by bioelectrical impedance vector analysis.
The sample consisted of 144 free-living patients (84 women and 60 men) with type 2 diabetes 60 to 84 y old and 209 age-matched controls (116 women and 93 men). Anthropometric measurements (weight; height; upper arm, hip, waist, and calf circumferences; biceps; triceps; and subscapular and suprailiac skinfolds) were taken. Blood samples for the assessment of plasma glucose and glycated hemoglobin were collected. The BMI, upper arm muscular area, and waist-to-hip ratio were calculated. Bioelectrical impedance vector analysis was applied. The analysis was performed in the entire diabetic sample and the healthy BMI-matched groups.
Compared with healthy subjects, patients had greater weight (P < 0.01 in women), higher BMI (P < 0.01 in women), smaller muscular area (P < 0.01 in men), and thicker skinfolds (P < 0.01 in women and men). Female and male patients showed larger phase angles (P < 0.01). Moreover, female patients showed a shorter vector length and lower resistance (P < 0.01) and male patients showed a higher reactance (P < 0.01). The BMI-matched analysis confirmed that patients were characterized by larger phase angles.
Older patients with type 2 diabetes were characterized by peculiar anthropometric and bioelectrical patterns, which can be related to their smaller appendicular muscular area and lower extracellular/intracellular water ratio.
本研究旨在通过生物电阻抗向量分析展示 2 型糖尿病老年患者与年龄和体重指数（BMI）匹配的健康对照者的身体成分特征。
该样本包括 144 名 2 型糖尿病患者（84 名女性和 60 名男性）和 209 名年龄匹配的对照组（116 名女性和 93 名男性），他们均为自由生活者。测量了体重、身高、上臂、臀部、腰部、小腿周长、肱二头肌、肱三头肌、肩胛下角和髂嵴皮褶厚度等人体测量学指标。采集了评估血浆葡萄糖和糖化血红蛋白的血样。计算了 BMI、上臂肌肉面积和腰臀比。进行了生物电阻抗向量分析。分析在整个糖尿病患者样本和健康 BMI 匹配组中进行。
与健康受试者相比，患者的体重更大（女性 P<0.01），BMI 更高（女性 P<0.01），肌肉面积更小（男性 P<0.01），皮褶更厚（女性和男性 P<0.01）。女性和男性患者的相位角更大（P<0.01）。此外，女性患者的向量长度较短，电阻较低（P<0.01），男性患者的电抗较高（P<0.01）。BMI 匹配分析证实，患者的特征是更大的相位角。
2 型糖尿病老年患者的人体测量和生物电阻抗特征独特，可能与他们较小的四肢肌肉面积和较低的细胞外/细胞内水比值有关。
