• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

节杆菌尼古丁降解菌的基因组序列

Genome sequence of a nicotine-degrading strain of Arthrobacter.

机构信息

State Key Laboratory of Microbial Metabolism and School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, People's Republic of China.

出版信息

J Bacteriol. 2012 Oct;194(20):5714-5. doi: 10.1128/JB.01370-12.

DOI:10.1128/JB.01370-12
PMID:23012289
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3458684/
Abstract

We announce a 4.63-Mb genome assembly of an isolated bacterium that is the first sequenced nicotine-degrading Arthrobacter strain. Nicotine catabolism genes of the nicotine-degrading plasmid pAO1 were predicted, but plasmid function genes were not found. These results will help to better illustrate the molecular mechanism of nicotine degradation by Arthrobacter.

摘要

我们宣布完成了一株孤立细菌的 4.63Mb 基因组组装，这是首个测序的尼古丁降解节杆菌菌株。预测了尼古丁降解质粒 pAO1 的尼古丁代谢基因，但未发现质粒功能基因。这些结果将有助于更好地阐明节杆菌尼古丁降解的分子机制。

相似文献

1
Genome sequence of a nicotine-degrading strain of Arthrobacter.节杆菌尼古丁降解菌的基因组序列
J Bacteriol. 2012 Oct;194(20):5714-5. doi: 10.1128/JB.01370-12.
2
Comparative genome analysis reveals the molecular basis of nicotine degradation and survival capacities of Arthrobacter.比较基因组分析揭示了节杆菌尼古丁降解和生存能力的分子基础。
Sci Rep. 2015 Feb 27;5:8642. doi: 10.1038/srep08642.
3
Sequence of the 165-kilobase catabolic plasmid pAO1 from Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system.来自嗜烟节杆菌的165千碱基分解代谢质粒pAO1的序列及一种依赖pAO1的尼古丁摄取系统的鉴定。
J Bacteriol. 2003 Mar;185(6):1976-86. doi: 10.1128/JB.185.6.1976-1986.2003.
4
Complete genome sequence and metabolic potential of the quinaldine-degrading bacterium Arthrobacter sp. Rue61a.喹哪啶降解菌 Arthrobacter sp. Rue61a 的全基因组序列和代谢潜能
BMC Genomics. 2012 Oct 6;13:534. doi: 10.1186/1471-2164-13-534.
5
s-triazine degrading bacterial isolate Arthrobacter sp. AK-YN10, a candidate for bioaugmentation of atrazine contaminated soil.降解 s-三嗪的细菌分离株节杆菌属 Arthrobacter sp. AK-YN10，是用于阿特拉津污染土壤生物强化的候选菌株。
Appl Microbiol Biotechnol. 2016 Jan;100(2):903-13. doi: 10.1007/s00253-015-6975-5. Epub 2015 Sep 25.
6
Microbiology and biochemistry of nicotine degradation.尼古丁降解的微生物学与生物化学
Appl Microbiol Biotechnol. 2006 Jan;69(5):493-8. doi: 10.1007/s00253-005-0226-0. Epub 2005 Dec 7.
7
Genome sequence of a novel nicotine-degrading strain, Pseudomonas geniculata N1.新型尼古丁降解菌株——假单胞菌 N1 的基因组序列。
J Bacteriol. 2012 Jul;194(13):3553-4. doi: 10.1128/JB.00625-12.
8
Gene structures and properties of enzymes of the plasmid-encoded nicotine catabolism of Arthrobacter nicotinovorans.嗜烟节杆菌质粒编码的烟碱分解代谢酶的基因结构与特性
J Mol Biol. 1998 Dec 18;284(5):1323-39. doi: 10.1006/jmbi.1998.2227.
9
A soil bacterial catabolic pathway on the move: Transfer of nicotine catabolic genes between genus megaplasmids and invasion by mobile elements.土壤细菌代谢途径的转移：尼古丁代谢基因在巨型质粒属之间的转移和移动元件的入侵。
J Biosci. 2020;45.
10
[Plasmids for biodegradation of 2,6-dimethylpyridine, 2,4-dimethylpyridine, and pyridine in strains of Arthrobacter].用于节杆菌菌株中2,6 - 二甲基吡啶、2,4 - 二甲基吡啶和吡啶生物降解的质粒
Mol Gen Mikrobiol Virusol. 1992 May-Jun(5-6):10-3.

引用本文的文献

1
Shaping the future of tobacco through microbial insights: a review of advances and applications.通过微生物学见解塑造烟草的未来：进展与应用综述
Front Bioeng Biotechnol. 2025 May 12;13:1548323. doi: 10.3389/fbioe.2025.1548323. eCollection 2025.
2
Reduction of nicotine content in tobacco through microbial degradation: research progress and potential applications.通过微生物降解降低烟草中的尼古丁含量：研究进展与潜在应用
Biotechnol Biofuels Bioprod. 2024 Dec 18;17(1):144. doi: 10.1186/s13068-024-02593-3.
3
Insights into Pharmacological Activities of Nicotine and 6-Hydroxy-L-nicotine, a Bacterial Nicotine Derivative: A Systematic Review.尼古丁和 6-羟基-L-烟碱（一种细菌衍生的尼古丁）的药理学活性研究进展：系统评价。
Biomolecules. 2023 Dec 23;14(1):23. doi: 10.3390/biom14010023.
4
Characterisation of the Paenarthrobacter nicotinovorans ATCC 49919 genome and identification of several strains harbouring a highly syntenic nic-genes cluster.Paenarthrobacter nicotinovorans ATCC 49919 基因组的特征描述及几株具有高度同源性 nic 基因簇菌株的鉴定。
BMC Genomics. 2023 Sep 11;24(1):536. doi: 10.1186/s12864-023-09644-3.
5
Biodegradation of Nicotine and TSNAs by Bacterium sp. Strain J54.细菌菌株J54对尼古丁和烟草特有亚硝胺的生物降解作用
Iran J Biotechnol. 2021 Jul 1;19(3):e2812. doi: 10.30498/ijb.2021.240460.2812. eCollection 2021 Jul.
6
Isolation of a 3-hydroxypyridine degrading bacterium, Agrobacterium sp. DW-1, and its proposed degradation pathway.一株3-羟基吡啶降解菌——根癌农杆菌DW-1的分离及其推测的降解途径。
AMB Express. 2019 May 17;9(1):65. doi: 10.1186/s13568-019-0782-9.
7
Characterization of a Novel Nicotine Degradation Gene Cluster in TY and Its Evolutionary Analysis.TY中一个新型尼古丁降解基因簇的表征及其进化分析。
Front Microbiol. 2017 Mar 9;8:337. doi: 10.3389/fmicb.2017.00337. eCollection 2017.
8
Comparative genome analysis reveals the molecular basis of nicotine degradation and survival capacities of Arthrobacter.比较基因组分析揭示了节杆菌尼古丁降解和生存能力的分子基础。
Sci Rep. 2015 Feb 27;5:8642. doi: 10.1038/srep08642.
9
Genome Sequence of a Newly Isolated Nicotine-Degrading Bacterium, Ochrobactrum sp. SJY1.新分离的尼古丁降解细菌苍白杆菌属SJY1的基因组序列
Genome Announc. 2014 Jul 24;2(4):e00720-14. doi: 10.1128/genomeA.00720-14.
10
Current status on biochemistry and molecular biology of microbial degradation of nicotine.微生物降解尼古丁的生物化学与分子生物学研究现状
ScientificWorldJournal. 2013 Dec 29;2013:125385. doi: 10.1155/2013/125385. eCollection 2013.

本文引用的文献

1
Genomic analysis of Pseudomonas putida: genes in a genome island are crucial for nicotine degradation.假单胞菌的基因组分析：基因组岛上的基因对于尼古丁的降解至关重要。
Sci Rep. 2012;2:377. doi: 10.1038/srep00377. Epub 2012 Apr 23.
2
A novel NADH-dependent and FAD-containing hydroxylase is crucial for nicotine degradation by Pseudomonas putida.一株新型依赖 NADH 和含 FAD 的羟化酶对假单胞菌属降解尼古丁至关重要。
J Biol Chem. 2011 Nov 11;286(45):39179-87. doi: 10.1074/jbc.M111.283929. Epub 2011 Sep 23.
3
Novel nicotine oxidoreductase-encoding gene involved in nicotine degradation by Pseudomonas putida strain S16.恶臭假单胞菌S16菌株中参与尼古丁降解的新型尼古丁氧化还原酶编码基因。
Appl Environ Microbiol. 2009 Feb;75(3):772-8. doi: 10.1128/AEM.02300-08. Epub 2008 Dec 5.
4
NCBI Reference Sequences: current status, policy and new initiatives.NCBI参考序列：当前状态、政策及新举措。
Nucleic Acids Res. 2009 Jan;37(Database issue):D32-6. doi: 10.1093/nar/gkn721. Epub 2008 Oct 16.
5
Velvet: algorithms for de novo short read assembly using de Bruijn graphs.《天鹅绒：使用德布鲁因图进行从头短读长拼接的算法》
Genome Res. 2008 May;18(5):821-9. doi: 10.1101/gr.074492.107. Epub 2008 Mar 18.
6
The RAST Server: rapid annotations using subsystems technology.RAST服务器：使用子系统技术进行快速注释。
BMC Genomics. 2008 Feb 8;9:75. doi: 10.1186/1471-2164-9-75.
7
A novel gene, encoding 6-hydroxy-3-succinoylpyridine hydroxylase, involved in nicotine degradation by Pseudomonas putida strain S16.一个编码6-羟基-3-琥珀酰吡啶羟化酶的新基因，参与恶臭假单胞菌S16菌株对尼古丁的降解。
Appl Environ Microbiol. 2008 Mar;74(5):1567-74. doi: 10.1128/AEM.02529-07. Epub 2008 Jan 18.
8
Secrets of soil survival revealed by the genome sequence of Arthrobacter aurescens TC1.嗜金黄节杆菌TC1基因组序列揭示土壤生存秘密
PLoS Genet. 2006 Dec;2(12):e214. doi: 10.1371/journal.pgen.0020214.
9
Microbiology and biochemistry of nicotine degradation.尼古丁降解的微生物学与生物化学
Appl Microbiol Biotechnol. 2006 Jan;69(5):493-8. doi: 10.1007/s00253-005-0226-0. Epub 2005 Dec 7.
10
Sequence of the 165-kilobase catabolic plasmid pAO1 from Arthrobacter nicotinovorans and identification of a pAO1-dependent nicotine uptake system.来自嗜烟节杆菌的165千碱基分解代谢质粒pAO1的序列及一种依赖pAO1的尼古丁摄取系统的鉴定。
J Bacteriol. 2003 Mar;185(6):1976-86. doi: 10.1128/JB.185.6.1976-1986.2003.