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韩国成年人的25(OH)D状态及其25(OH)D的人口统计学和生活方式决定因素

25(OH)D status and demographic and lifestyle determinants of 25(OH)D among Korean adults.

作者信息

Choi Eun Young

机构信息

Department of Family Medicine, School of Medicine, Dankook University, South Korea 330-714.

出版信息

Asia Pac J Clin Nutr. 2012;21(4):526-35.

Abstract

PURPOSE

Vitamin D deficiency is a global health problem that is associated with increased risks of major diseases. This study investigated the status of 25-hydroxyvitamin D [25(OH)D] and its demographic and lifestyle determinants among Korean adults.

METHODS

A total of 5,847 adults who had participated in the Korean National Health and Nutrition Examination Survey of 2008 (KNHANES) were included in the present study. Stepwise linear regression analysis was performed to determine the demographic and lifestyle determinants of 25(OH)D concentration.

RESULTS

The weighted prevalence (standard error) of 25(OH)D deficiency (<20 ng/mL) was 49.9 (2.1)% among the males and 67.4 (1.7)% among the females. Severe 25(OH)D deficiencies (<10 ng/mL) were found in 5.7 (0.8)% of the males and 11.1 (1.0)% of the females. These peaked in spring and winter. Only 12.2 (1.1)% of the males and 6.4 (0.6)% of the females exhibited 25(OH)D sufficiency (>=30 ng/mL). The correlates with higher 25(OH)D concentration for both genders included summer, fall (vs spring), the 60s age group (vs 20s), rural residence (vs urban), moderate and vigorous physical activity (vs sedentary), alcohol consumption, and multivitamin supplementation. Higher education and unmarried status were inversely associated with 25(OH)D concentration for both genders. The strongest predictors of 25(OH)D concentration were season and residential area.

CONCLUSIONS

25(OH)D deficiency is a prevalent condition in Korea. Understanding the determinants of 25(OH)D can facilitate identification of persons at risk of 25(OH)D deficiency.

摘要

目的

维生素D缺乏是一个全球性的健康问题,与重大疾病风险增加相关。本研究调查了韩国成年人中25-羟基维生素D[25(OH)D]的状况及其人口统计学和生活方式决定因素。

方法

本研究纳入了2008年韩国国家健康与营养检查调查(KNHANES)中的5847名成年人。进行逐步线性回归分析以确定25(OH)D浓度的人口统计学和生活方式决定因素。

结果

男性中25(OH)D缺乏(<20 ng/mL)的加权患病率(标准误差)为49.9(2.1)%,女性为67.4(1.7)%。男性中5.7(0.8)%、女性中11.1(1.0)%存在严重25(OH)D缺乏(<10 ng/mL)。这些情况在春季和冬季达到峰值。只有12.2(1.1)%的男性和6.4(0.6)%的女性表现出25(OH)D充足(>=30 ng/mL)。与两性较高25(OH)D浓度相关的因素包括夏季、秋季(与春季相比)、60岁年龄组(与20岁相比)、农村居住(与城市相比)、中度和剧烈体育活动(与久坐相比)、饮酒以及服用多种维生素。较高的教育程度和未婚状态与两性的25(OH)D浓度呈负相关。25(OH)D浓度的最强预测因素是季节和居住地区。

结论

25(OH)D缺乏在韩国是一种普遍情况。了解25(OH)D的决定因素有助于识别有25(OH)D缺乏风险的人群。

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