Ashkenazi J, Feldberg D, Dicker D, Shelef M, Goldman G A, Goldman J A
Sherman Fertility Institute, Golda Meir Medical Center, Hashron Hospital, Petah Tikva, Israel.
Eur J Obstet Gynecol Reprod Biol. 1990 Jan-Feb;34(1-2):97-101. doi: 10.1016/0028-2243(90)90012-p.
In the event of non-fertilization of oocytes at the first insemination, repeat insemination is often successful in the IVF procedure. Nevertheless, the value of reinsemination is still controversial. In 56 out of 132 (42%) women treated in our IVF-ET Unit for mechanical infertility by identical induction and aspiration protocols, reinsemination of one or more ova was required. They were divided into two groups. Group I: 79 oocytes from 32 women who were reinseminated with initial semen 24 hours following primary insemination. Group II: 57 oocytes from 24 patients who were reinseminated with fresh semen 24 hours following primary insemination. Fertilization, cleavage and pregnancy rates differed significantly in group I as compared to group II (21.2%, 37.3%, p less than 0.005; 18.6%, 31.9%, p less than 0.001; 18.4%, 29.1%, p less than 0.001). We conclude that reinsemination is a beneficial procedure in cases of non-fertilization of oocytes at the first insemination. Furthermore, the use of fresh semen is preferred to achieve higher fertilization, cleavage and pregnancy rates.
在首次授精时若卵母细胞未受精，在体外受精程序中重复授精往往会成功。然而，重复授精的价值仍存在争议。在我们的体外受精 - 胚胎移植单元中，按照相同的诱导和抽吸方案治疗机械性不孕症的132名女性中有56名（42%）需要对一个或多个卵子进行重复授精。她们被分为两组。第一组：32名女性的79个卵母细胞，在初次授精后24小时用初始精液进行重复授精。第二组：24名患者的57个卵母细胞，在初次授精后24小时用新鲜精液进行重复授精。与第二组相比，第一组的受精率、卵裂率和妊娠率有显著差异（分别为21.2%、3女7.3%，p小于0.005；18.6%、31.9%，p小于0.001；18.4%、29.1%，p小于0.001）。我们得出结论，在首次授精时卵母细胞未受精的情况下，重复授精是一种有益的程序。此外，为了获得更高的受精率、卵裂率和妊娠率，优先使用新鲜精液。
