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使用离轴孔径照明的高数值孔径反射模式相干衍射显微镜。

High numerical aperture reflection mode coherent diffraction microscopy using off-axis apertured illumination.

作者信息

Gardner Dennis F, Zhang Bosheng, Seaberg Matthew D, Martin Leigh S, Adams Daniel E, Salmassi Farhad, Gullikson Eric, Kapteyn Henry, Murnane Margaret

机构信息

JILA, University of Colorado, 440 UCB, Boulder, Colorado 80309-0440, USA.

出版信息

Opt Express. 2012 Aug 13;20(17):19050-9. doi: 10.1364/OE.20.019050.

DOI:10.1364/OE.20.019050
PMID:23038545
Abstract

We extend coherent diffraction imaging (CDI) to a high numerical aperture reflection mode geometry for the first time. We derive a coordinate transform that allows us to rewrite the recorded far-field scatter pattern from a tilted object as a uniformly spaced Fourier transform. Using this approach, FFTs in standard iterative phase retrieval algorithms can be used to significantly speed up the image reconstruction times. Moreover, we avoid the isolated sample requirement by imaging a pinhole onto the specimen, in a technique termed apertured illumination CDI. By combining the new coordinate transformation with apertured illumination CDI, we demonstrate rapid high numerical aperture imaging of samples illuminated by visible laser light. Finally, we demonstrate future promise for this technique by using high harmonic beams for high numerical aperture reflection mode imaging.

摘要

我们首次将相干衍射成像(CDI)扩展到高数值孔径反射模式几何结构。我们推导了一种坐标变换,使我们能够将倾斜物体记录的远场散射图案重写为均匀间隔的傅里叶变换。使用这种方法,标准迭代相位恢复算法中的快速傅里叶变换(FFT)可用于显著加快图像重建时间。此外,我们通过在一种称为孔径照明CDI的技术中对针孔成像到样本上,避免了对孤立样本的要求。通过将新的坐标变换与孔径照明CDI相结合,我们展示了对可见激光照射的样本进行快速高数值孔径成像。最后,我们通过使用高谐波光束进行高数值孔径反射模式成像,展示了该技术的未来前景。

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