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回肠新膀胱:100多例连续病例的经验与结果

The ileal neobladder: experience and results of more than 100 consecutive cases.

作者信息

Wenderoth U K, Bachor R, Egghart G, Frohneberg D, Miller K, Hautmann R E

机构信息

Department of Urology, University of Ulm, Federal Republic of Germany.

出版信息

J Urol. 1990 Mar;143(3):492-6; discussion 496-7. doi: 10.1016/s0022-5347(17)40000-0.

Abstract

The ileal neobladder produces a completely detubularized, low pressure, high capacity reservoir constructed from ileum without any valves. From April 1986 through May 1989, 113 patients underwent this procedure at our institution. Of these patients 99 underwent simultaneous radical cystectomy for bladder cancer and 14 underwent bladder augmentation. The mean postoperative followup was 14.4 months, with a range of 1 to 36 months. There was no perioperative mortality. However, 7 patients died more than 2 months postoperatively: 5 of tumor progression, 1 of pneumonia and severe metabolic acidosis, and 1 of septicemia of unknown cause. Reoperation was necessary in only 13 patients; 10 patients required urethrotomy or dilation of urethral strictures. Day and night continence was preserved in 82.1% of all patients. Stress incontinence, which must be corrected by an artificial sphincter, was found in 4 patients (4.2%) and night-time incontinence that required an external device occurred in 5 (5.3%). Eight patients (8.4%) with mild stress incontinence required no further treatment. Pressure waves exceeding 22 cm. water seldom occurred and then only at maximum capacity. Our experience with this relatively simple system without a nipple is an overwhelming success. The need for reoperation is extraordinarily low and the high reservoir capacity results in continence from the beginning in most patients. The concept is sound and offers a genuine alternative to any form of cutaneous urinary diversion with an incidence of complications not higher than after standard supravesical urinary diversion.

摘要

回肠新膀胱是一个完全去管状化、低压、大容量的贮尿囊,由回肠构建而成,没有任何瓣膜。从1986年4月至1989年5月,我院有113例患者接受了该手术。其中99例因膀胱癌同期行了根治性膀胱切除术,14例行膀胱扩大术。术后平均随访14.4个月,范围为1至36个月。围手术期无死亡病例。然而,7例患者术后2个月以上死亡:5例死于肿瘤进展,1例死于肺炎和严重代谢性酸中毒,1例死于不明原因的败血症。仅13例患者需要再次手术;10例患者需要行尿道切开术或尿道狭窄扩张术。所有患者中82.1%保持了日间和夜间控尿。4例患者(4.2%)出现压力性尿失禁,需通过人工括约肌矫正,5例患者(5.3%)出现夜间尿失禁,需使用外部装置。8例轻度压力性尿失禁患者(8.4%)无需进一步治疗。很少出现超过22 cm水柱的压力波,且仅在最大容量时出现。我们使用这种相对简单的无乳头系统的经验取得了巨大成功。再次手术的需求极低,高容量贮尿囊使大多数患者从一开始就能实现控尿。该理念合理,为任何形式的皮肤造口尿流改道术提供了真正的替代方案,并发症发生率不高于标准的膀胱上尿流改道术。

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