Jakovleva L S, Mazurenko N P
Neoplasma. 1979;26(4):393-6.
Intramuscular (i.m.) injection of RAV-49 into 1--3 day-old chickens infected with Marek's disease herpes virus (MDHV) by contact led to exceedingly high rate of Marek's disease (MD) incidence. According to the data obtained in three experiments 52 out of 108 (48.1%) chickens fell ill in this group. While in the group uninfected with RAV-49 but contactly infected with MDV-Kekava there were only 11 out of 102, (10.7%) incidences. Simultaneous inoculations of RAV-49 and MDV had no effect on MD morbidity. Increased susceptibility of i.m. RAV-49-infected and contactly MDV-infected chickens to MD was abolished by simultaneous inoculation of RAV-49 and herpes virus of turkeys (HVT).
对通过接触感染马立克氏病疱疹病毒（MDHV）的1至3日龄雏鸡进行肌肉注射RAV - 49，导致马立克氏病（MD）发病率极高。根据三个实验获得的数据，该组108只鸡中有52只（48.1%）发病。而在未感染RAV - 49但通过接触感染MDV - 凯卡瓦的组中，102只鸡中只有11只（10.7%）发病。同时接种RAV - 49和MDV对MD发病率没有影响。同时接种RAV - 49和火鸡疱疹病毒（HVT）可消除肌肉注射RAV - 49感染且接触感染MDV的鸡对MD的易感性增加。
