Department of Neonatology, Dr Sami Ulus Maternity and Children Research and Training Hospital, Ankara, Turkey.
Indian J Pediatr. 2013 Jul;80(7):555-9. doi: 10.1007/s12098-012-0852-3. Epub 2012 Oct 4.
To analyze non benign neonatal arrhythmias (NA) observed in a tertiary neonatal intensive care unit (NICU).
From June 2006 through July 2011, newborns admitted to the NICU for NA or diagnosed as NA after hospitalization were evaluated retrospectively. The newborns with non benign NA were included in the study.
During the study period, the incidence of non-benign NA was 0.7 % (n = 55/7880). The mean age at diagnosis was 16.7 ± 1.8 d ranging from 1 d to 90 d. The most common type was supraventricular arrhythmia (SVT) with an incidence of 0.3 %. Univariate analyses showed that there were significant differences between the survived and died infants according types of congenital heart disease (CHD), electrolyte imbalance, and arrhythmias. The mortality rates were higher among infants with obstructive type left-to right shunt and common mixing type CHD. The most dangerous type of electrolyte imbalance was hyperkalemia.
Many arrhythmias could not be noticed at neonatal period even in NICU, implying that it is increasingly important for the physician to be aware of the etiology, development, and natural history of these arrhythmias.
分析在一家三级新生儿重症监护病房(NICU)中观察到的非良性新生儿心律失常(NA)。
从 2006 年 6 月至 2011 年 7 月,对因 NA 入住 NICU 或住院后被诊断为 NA 的新生儿进行回顾性评估。将患有非良性 NA 的新生儿纳入研究。
在研究期间,非良性 NA 的发生率为 0.7%(n=55/7880)。诊断时的平均年龄为 16.7±1.8 天,范围为 1 天至 90 天。最常见的类型是室上性心律失常(SVT),发生率为 0.3%。单因素分析显示,先天性心脏病(CHD)类型、电解质失衡和心律失常在存活和死亡婴儿之间存在显著差异。左向右分流阻塞型和常见混合型 CHD 患儿的死亡率较高。最危险的电解质失衡类型是高钾血症。
即使在 NICU 中,许多心律失常也可能在新生儿期无法察觉,这意味着医生越来越需要了解这些心律失常的病因、发展和自然病史。