Williams D F, Mieler W F, Jaffe G J, Robertson D M, Hendrix L
Department of Ophthalmology, Medical College of Wisconsin, Milwaukee 53226.
Br J Ophthalmol. 1990 Jan;74(1):43-6. doi: 10.1136/bjo.74.1.43.
Adequate treatment of juxtapapillary melanomas with episcleral plaque brachytherapy using lower energy radiation sources may be difficult because of uncertainties regarding the relationship of the plaque to the optic nerve and tumour base. We obtained magnetic resonance images of a dummy plaque placed in a juxtapapillary location in cadaver specimens. Although it is possible to place a plaque in close association with the optic nerve sheath, a tissue barrier exists which may prevent actual contact between the plaque and nerve. Posterior tilting of the plaque may also occur. Because of these uncertainties regarding plaque placement, juxtapapillary melanomas should be considered a distinct subgroup when evaluating the efficacy of radioactive plaque brachytherapy in the treatment of choroidal melanoma.
使用低能量放射源的巩膜外斑块近距离放射疗法对近乳头黑色素瘤进行充分治疗可能会很困难，因为斑块与视神经和肿瘤基底的关系存在不确定性。我们获取了放置在尸体标本近乳头位置的模拟斑块的磁共振图像。虽然有可能将斑块放置在与视神经鞘紧密相邻的位置，但存在一个组织屏障，这可能会阻止斑块与神经实际接触。斑块也可能发生向后倾斜。由于斑块放置存在这些不确定性，在评估放射性斑块近距离放射疗法治疗脉络膜黑色素瘤的疗效时，近乳头黑色素瘤应被视为一个独特的亚组。
