Berger H A, Morganroth M L
Department of Internal Medicine, University of Michigan, Ann Arbor.
Chest. 1990 Mar;97(3):731-5. doi: 10.1378/chest.97.3.731.
We retrospectively investigated if the clinical course of complicated parapneumonic effusions was altered by treatment with immediate drainage plus antibiotics vs antibiotics alone. The two groups of patients had no significant differences in age, duration of symptoms prior to hospitalization, initial maximum temperature, WBC count, or characteristics of the pleural fluid. There were no differences in the duration of hospitalization, fever, elevated WBC count, intravenous antibiotic therapy, or the time for roentgenographic resolution of the effusions. There was one death in each group. The infection of the pleural space resolved in 13 of 16 patients treated with antibiotics alone. No recurrence of the infection of the pleural space occurred in these patients. Antibiotics alone were not sufficient in two cases which eventually required chest tube drainage. Therefore, not all complicated parapneumonic effusions require drainage. A prospective study is required to determine if chest tube drainage should be part of the initial management of complicated parapneumonic effusions.
我们进行了回顾性研究,比较即刻引流加抗生素治疗与单纯抗生素治疗对复杂性类肺炎性胸腔积液临床病程的影响。两组患者在年龄、住院前症状持续时间、初始最高体温、白细胞计数或胸腔积液特征方面无显著差异。在住院时间、发热、白细胞计数升高、静脉抗生素治疗或胸腔积液影像学吸收时间方面也无差异。每组均有1例死亡。单纯使用抗生素治疗的16例患者中,13例胸腔感染得到解决。这些患者未出现胸腔感染复发。有2例单纯使用抗生素治疗不足,最终需要胸腔置管引流。因此,并非所有复杂性类肺炎性胸腔积液都需要引流。需要进行前瞻性研究以确定胸腔置管引流是否应作为复杂性类肺炎性胸腔积液初始治疗的一部分。