Centre for Psychophysics, Psychophysiology, and Psychopharmacology, Brain & Behaviour Research Institute, and School of Psychology, University of Wollongong, Wollongong NSW 2522, Australia.
Int J Psychophysiol. 2013 Mar;87(3):279-88. doi: 10.1016/j.ijpsycho.2012.09.016. Epub 2012 Oct 13.
Ongoing low-frequency EEG activity has long been associated with ERP components and their cognitive processing interpretations, yet few studies have directly investigated the prestimulus low-frequency EEG-ERP relationships, particularly within the auditory domain. The present study assessed the delta (1-3 Hz) and theta (4-7 Hz) bands individually, and their prestimulus influence on five subsequent components (P1, N1, P2, N2, and P3) within an equiprobable auditory Go/NoGo paradigm. At the nine central sites, accepted trials were sorted according to their ascending vertex prestimulus spectral band amplitude, and ERPs were derived from the upper and lower sorted thirds. The within-subjects analyses included amplitudes and latencies for both Go and NoGo responses, and Go response speed. Only component amplitudes showed effects of high/low prestimulus EEG level. Delta globally modulated the five components - all amplitudes were more positive with high prestimulus delta, regardless of stimulus condition. Theta did not influence P1, but inversely modulated P2 and P3 regionally, and produced stimulus-specific effects in N1, N2, and P3. Low prestimulus theta produced greater NoGo N2 and Go P3, and reduced NoGo P3 responses, each of these suggesting appropriately enhanced cognitive processing. Taken together, these effect patterns differentially implicate prestimulus delta and theta band activity in the determination of ERP component amplitudes and the cognitive processing associated with them.
持续的低频 EEG 活动长期以来一直与 ERP 成分及其认知加工解释相关联，但很少有研究直接研究刺激前低频 EEG-ERP 关系，特别是在听觉领域。本研究分别评估了 delta（1-3 Hz）和 theta（4-7 Hz）频段，以及它们在等概率听觉 Go/NoGo 范式中对五个后续成分（P1、N1、P2、N2 和 P3）的刺激前影响。在九个中央部位，根据顶点刺激前光谱带幅度对接受的试验进行排序，并从上下三分之一部分导出 ERP。在被试内分析中，包括 Go 和 NoGo 反应的幅度和潜伏期，以及 Go 反应速度。只有成分幅度受到高/低刺激前 EEG 水平的影响。Delta 全局调节五个成分-无论刺激条件如何，高刺激前 delta 时所有幅度都更正向。Theta 不影响 P1，但局部调节 P2 和 P3，并且在 N1、N2 和 P3 中产生刺激特异性效应。低刺激前 theta 产生更大的 NoGo N2 和 Go P3，并减少 NoGo P3 反应，这些都表明适当增强了认知加工。总之，这些效应模式不同程度地暗示了刺激前 delta 和 theta 频段活动在确定 ERP 成分幅度和与之相关的认知加工中的作用。
