Section on Hematology and Oncology, Wake Forest Baptist Health, Winston-Salem, NC, USA.
Cancer Metastasis Rev. 2013 Jun;32(1-2):63-76. doi: 10.1007/s10555-012-9405-5.
Animal models have been invaluable in the efforts to better understand and ultimately treat patients suffering from leukemia. While important insights have been gleaned from these models, limitations must be acknowledged. In this review, we will highlight the various animal models of leukemia and describe their contributions to the improved understanding and treatment of these cancers.
动物模型在努力更好地理解和最终治疗白血病患者方面发挥了不可估量的作用。虽然从这些模型中获得了重要的见解,但必须承认存在局限性。在这篇综述中,我们将重点介绍各种白血病动物模型,并描述它们对改善这些癌症的理解和治疗的贡献。