McMahon Jeremy D, Wong Ling Siew, Crowther John, Taylor William M, McManners Joseph, Devine John C, Wales Craig, Maciver Colin
Southern General Hospital, Glasgow G51 4TF, United Kingdom.
Br J Oral Maxillofac Surg. 2013 Jul;51(5):389-93. doi: 10.1016/j.bjoms.2012.09.018. Epub 2012 Oct 22.
Local recurrence remains the most important sign of relapse of disease after treatment of advanced cancer of the maxilla and sinonasal region. In this retrospective study we describe patterns of recurrence in a group of patients who had had open resection for cancer of the sinonasal region and posterior maxillary alveolus with curative intent. Casenotes and imaging studies were reviewed to find out the pattern of any relapse, with particular reference to local recurrence. The minimum follow-up period was 12 months. Of 50 patients a total of 16 developed recurrences, 11 of which were local. Of those 11, a total of 8 were in posterior and superior locations (the orbit, the infratemporal and pterygopalatine fossas, the traversing neurovascular canals of the body of the sphenoid to the cavernous sinus, the Gasserian ganglion, and the dura of the middle cranial fossa). Advanced cancer of the midface often equates with disease at the skull base. Treatment, including surgical tactics, should reflect that.
局部复发仍然是上颌骨和鼻窦区域晚期癌症治疗后疾病复发的最重要标志。在这项回顾性研究中，我们描述了一组因鼻窦区域和上颌后牙槽癌症而接受根治性开放切除术的患者的复发模式。回顾病历和影像学研究以找出任何复发模式，特别关注局部复发。最短随访期为12个月。50例患者中共有16例出现复发，其中11例为局部复发。在这11例中，共有8例位于后部和上部位置（眼眶、颞下窝和翼腭窝、蝶骨体至海绵窦的穿行神经血管通道、三叉神经节以及中颅窝硬脑膜）。面中部的晚期癌症通常等同于颅底疾病。治疗，包括手术策略，应体现这一点。
