Department of Microbiology, PSGVP Mandal's ASC College, Shahada, District Nandurbar, 425405 Maharashtra India.
Indian J Microbiol. 2010 Jun;50(2):179-82. doi: 10.1007/s12088-010-0021-1. Epub 2010 Apr 29.
During stationary phase of growth under low stress of iron in succinic acid medium, Alcaligenes feacalis BCCM ID 2374 produced microbial iron chelators. Increase in iron concentration supported bacterial growth but suppressed siderophores production, 1 μM and 2 μM of iron was optimum for maximum siderophore yield, i.e. 354 and 360 μg/ml in untreated and deferrated medium, respectively. Threshold level of iron, which suppressed siderophores production in A. feacalis BCCM ID 2374, was 20 μM. Ten micromoles and above concentration of CuCl(2) and CoCl(2), and 20 μM of MgCl(2), MgSO(4), ZnCl(2) and ZnSO(4) severely affected siderophores production.
在琥珀酸培养基低铁应激的静止生长阶段,产碱杆菌 BCCM ID 2374 产生微生物铁螯合剂。铁浓度的增加支持细菌生长,但抑制了铁载体的产生,1 μM 和 2 μM 的铁是获得最大铁载体产量的最佳浓度,即在未处理和去铁培养基中分别为 354 和 360 μg/ml。抑制产碱杆菌 BCCM ID 2374 中铁载体产生的铁阈值水平为 20 μM。10 微摩尔及以上浓度的 CuCl(2)和 CoCl(2),以及 20 μM 的 MgCl(2)、MgSO(4)、ZnCl(2)和 ZnSO(4)严重影响铁载体的产生。