Wiwanitkit Viroj
Wiwanitkit House, Bangkhae, Bangkok, Thailand 10160.
Indian J Hematol Blood Transfus. 2010 Mar;26(1):6-7. doi: 10.1007/s12288-010-0003-9. Epub 2010 Aug 4.
Rh antigen is a widely studied but not already known antigen. RH48 (JAL) is a low-incidence Rh antigen of unknown molecular background and is proposed for association with weakened expression of RhCE antigens. Here, the author performed a bioinformatics approach to study the probability of JAL mutation. It can be shown that JAL is a highly unstable molecule that is prone for mutation.
Rh抗原是一种经过广泛研究但尚不为人知的抗原。RH48(JAL)是一种分子背景未知的低发生率Rh抗原,有人提出它与RhCE抗原表达减弱有关。在此,作者采用生物信息学方法研究JAL突变的可能性。结果表明,JAL是一种高度不稳定且易于发生突变的分子。