Sutherland R J, McDonald R J
Department of Psychology, University of Lethbridge, Alta., Canada.
Behav Brain Res. 1990 Feb 12;37(1):57-79. doi: 10.1016/0166-4328(90)90072-m.
Five experiments were conducted to compare the contribution of the hippocampal formation and amygdala to mnemonic processes. The performance of rats with damage to the hippocampal formation or amygdala was examined in tests of visual and olfactory non-matching-to-sample with familiar items, cross-modal association, gustatory neophobia, topographical memory, autonomic conditioning to context, and configural discriminations. Neither lesion affects non-matching-to-sample performance. An intact hippocampal formation, but not amygdala, is necessary for cross-modal association between vision and olfaction, topographical memory, conditioning to context, and configural discrimination learning. Amygdala damage disrupted gustatory neophobia and may have impaired learning an association between an auditory cue and food reward.
进行了五项实验，以比较海马结构和杏仁核在记忆过程中的作用。在对熟悉物品的视觉和嗅觉非匹配样本测试、跨模态关联、味觉新恐惧症、地形记忆、对环境的自主条件反射以及构型辨别测试中，检测了海马结构或杏仁核受损大鼠的表现。两种损伤均不影响非匹配样本的表现。完整的海马结构而非杏仁核，对于视觉和嗅觉之间的跨模态关联、地形记忆、对环境的条件反射以及构型辨别学习是必需的。杏仁核损伤破坏了味觉新恐惧症，并且可能损害了学习听觉线索与食物奖励之间关联的能力。
