Murali Y K, Chandra Ramesh, Murthy P S
Dr B.R. Ambedkar Center for Biomedical Research, University of Delhi, 110007 Delhi.
Indian J Clin Biochem. 2004 Jul;19(2):202-4. doi: 10.1007/BF02894285.
Water extract of dry fruits ofTerminalia chebula (Hindi-Harda, Telugu-Karakkaya) at a dose of 200 mg/kg body weight improved the glucose tolerance as indicated by 44% of reduction in the peak blood glucose at 2(nd) hour in glucose tolerance test in diabetic (streptozotocin induced) rats. Treatment of diabetic rats with an initial fasting blood glucose of 253±9.4 mg/dl daily once with the water extract (200 mg/kg) for two weeks brought down the fasting blood glucose to 123±8.4 mg/dl which is only slightly above the normal value. These results indicate that water extract of Terminalia chebula improves glucose tolerance and brings down fasting blood glucose in diabetic rats.
诃子（印地语 - 哈达，泰卢固语 - 卡拉卡亚）干果的水提取物，以200毫克/千克体重的剂量给药，改善了葡萄糖耐量，这在糖尿病（链脲佐菌素诱导）大鼠的葡萄糖耐量试验中表现为第2小时时血糖峰值降低了44%。对初始空腹血糖为253±9.4毫克/分升的糖尿病大鼠，每天一次用水提取物（200毫克/千克）治疗两周后，空腹血糖降至123±8.4毫克/分升，仅略高于正常值。这些结果表明，诃子水提取物可改善糖尿病大鼠的葡萄糖耐量并降低空腹血糖。
