Boumba Vassiliki A, Georgiadis Minas, Mirescu Nikolae, Vougiouklakis Theodore
Department of Forensic Medicine & Toxicology Medical School, University of Ioannina, 45110, Ioaninna, Greece.
J Forensic Sci. 2013 Mar;58(2):425-31. doi: 10.1111/1556-4029.12014. Epub 2012 Oct 26.
In this retrospective study, we report the epidemiological characteristics of all poisoning deaths in Epirus, Greece, from 1998 to 2010; we present the toxicological findings and the statistical evaluation of the results. This is the first detailed scientific report on all the officially certified poisoning deaths concerning part of the Greek population. A total of 126 poisoning fatalities were recorded, 67 of them being mono-intoxications (53.2%). The cause of poisoning was as follows: drugs of abuse (60%); carbon monoxide (19.8%); pesticides (9.5%); corrosives (4.8%); pharmaceuticals (4.8%); and spider bite (0.8%). The most frequently detected poisonous substances were as follows: heroin (65 cases), ethanol (55), benzodiazepines (42), carbon monoxide (25), cocaine (17), cannabinoids (17) and pesticides (12). Increasing tendency in poisoning death rates was recorded, due to an increase in accidental poisoning deaths attributed mainly to drugs of abuse (total, accidental, and drugs-of-abuse poisoning death rates per 100,000 inhabitants per year were 1.87, 1.19, and 0.79, respectively, in the period 1998-2002 and 3.97, 3.41, and 2.55, respectively, in the period 2007-2010).
在这项回顾性研究中,我们报告了1998年至2010年希腊伊庇鲁斯地区所有中毒死亡的流行病学特征;我们展示了毒理学发现以及结果的统计评估。这是关于希腊部分人口中所有官方认证中毒死亡情况的首份详细科学报告。共记录了126例中毒死亡病例,其中67例为单一中毒(53.2%)。中毒原因如下:滥用药物(60%);一氧化碳(19.8%);农药(9.5%);腐蚀性物质(4.8%);药品(4.8%);以及蜘蛛咬伤(0.8%)。最常检测到的有毒物质如下:海洛因(65例)、乙醇(55例)、苯二氮䓬类药物(42例)、一氧化碳(25例)、可卡因(17例)、大麻素(17例)和农药(12例)。由于主要归因于滥用药物的意外中毒死亡人数增加,中毒死亡率呈上升趋势(1998 - 2002年期间,每10万居民每年的中毒总死亡率、意外中毒死亡率和滥用药物中毒死亡率分别为1.87、1.19和0.79,而在2007 - 2010年期间分别为3.97、3.41和2.55)。