植物化学物质对胰腺癌的化学预防作用。
Pancreatic cancer chemoprevention by phytochemicals.
作者信息
Boreddy Srinivas Reddy, Srivastava Sanjay K
机构信息
Department of Biomedical Sciences and Cancer Biology Center, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.
Department of Biomedical Sciences and Cancer Biology Center, Texas Tech University Health Sciences Center, Amarillo, TX 79106, USA.
出版信息
Cancer Lett. 2013 Jun 28;334(1):86-94. doi: 10.1016/j.canlet.2012.10.020. Epub 2012 Oct 27.
Abstract
Pancreatic cancer is fourth leading cause of cancer-related deaths in the United States of America. In spite of recent advances in the current therapeutic modalities such as surgery, radiation and chemotherapy patients, the average five year survival rate remains still less than 5%. Recently, compounds from natural sources receive ample of attention as anti-cancer agents. Many epidemiological studies published over the past few decades provide a strong correlation between consumption of vegetables, fruits or plant derived products and reduced incidence of cancer. The present review focuses on the potential antitumor effects of various natural products.
摘要
胰腺癌是美国癌症相关死亡的第四大主要原因。尽管目前在手术、放疗和化疗等治疗方式上取得了进展，但患者的平均五年生存率仍低于5%。最近，天然来源的化合物作为抗癌剂受到了广泛关注。过去几十年发表的许多流行病学研究表明，食用蔬菜、水果或植物衍生产品与降低癌症发病率之间存在密切关联。本综述重点关注各种天然产物的潜在抗肿瘤作用。
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