Rodríguez-Negrete Elda Victoria, Morales-González Ángel, Madrigal-Santillán Eduardo Osiris, Sánchez-Reyes Karina, Álvarez-González Isela, Madrigal-Bujaidar Eduardo, Valadez-Vega Carmen, Chamorro-Cevallos German, Garcia-Melo Luis Fernando, Morales-González José A
Servicio de Gastroenterología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 06720, Mexico.
Laboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Mexico City C.P. 11340, Mexico.
Plants (Basel). 2024 Feb 15;13(4):523. doi: 10.3390/plants13040523.
Inflammation is the immune system's first biological response to infection, injury, or irritation. Evidence suggests that the anti-inflammatory effect is mediated by the regulation of various inflammatory cytokines, such as nitric oxide, interleukins, tumor necrosis factor alpha-α, interferon gamma-γ, as well as the non-cytokine mediator, prostaglandin E2. Currently, the mechanism of action and clinical usefulness of phytochemicals is known; their action on the activity of cytokines, free radicals, and oxidative stress. The latter are of great relevance in the development of diseases, such that the evidence collected demonstrates the beneficial effects of phytochemicals in maintaining health. Epidemiological evidence indicates that regular consumption of fruits and vegetables is related to a low risk of developing cancer and other chronic diseases.
炎症是免疫系统对感染、损伤或刺激的首要生物学反应。有证据表明，抗炎作用是由多种炎性细胞因子的调节介导的，如一氧化氮、白细胞介素、肿瘤坏死因子α-α、干扰素γ-γ，以及非细胞因子介质前列腺素E2。目前，植物化学物质的作用机制和临床效用是已知的；它们对细胞因子活性、自由基和氧化应激的作用。后者在疾病发展中具有重要意义，因此收集到的证据表明植物化学物质在维持健康方面具有有益作用。流行病学证据表明，经常食用水果和蔬菜与患癌症和其他慢性病的低风险有关。
