无义抑制基因可部分恢复酵母中无义突变等位基因mRNA水平的降低。
Nonsense suppressors partially revert the decrease of the mRNA level of a nonsense mutant allele in yeast.
作者信息
Gozalbo D, Hohmann S
机构信息
Institut für Mikrobiologie, Technische Hochschule Darmstadt, Federal Republic of Germany.
出版信息
Curr Genet. 1990 Jan;17(1):77-9. doi: 10.1007/BF00313252.
PMID:2311129
Abstract
suc2 degrees is a naturally occurring amber mutant allele of the yeast invertase structural gene SUC2. Strains carrying suc2 degrees had only 10% of the wild type invertase-specific mRNA level. Amber suppressors, which allowed suc2 degree strains to ferment sucrose caused an increase of the SUC-specific mRNA level.
摘要
suc2°是酵母转化酶结构基因SUC2的一个天然存在的琥珀突变等位基因。携带suc2°的菌株的野生型转化酶特异性mRNA水平仅为10%。琥珀抑制子使suc2°菌株能够发酵蔗糖，导致SUC特异性mRNA水平升高。
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