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亚洲癌症患者的支持性、姑息性和终末期护理:2012 年亚洲肿瘤峰会制定的资源分层指南。

Supportive, palliative, and end-of-life care for patients with cancer in Asia: resource-stratified guidelines from the Asian Oncology Summit 2012.

机构信息

International Observatory on End of Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster, UK.

出版信息

Lancet Oncol. 2012 Nov;13(11):e492-500. doi: 10.1016/S1470-2045(12)70380-7.

Abstract

The burden of cancer in Asia is high; 6·1 million new cases were diagnosed in the continent in 2008, which accounted for 48% of new cases worldwide. Deaths from cancer are expected to continue to rise because of ageing populations and modifiable risk factors such as tobacco and alcohol use, diet, and obesity. Most patients who are diagnosed with cancer in Asia have advanced disease that is not amenable to curative treatment, which means that they are likely to have pain and other symptoms and psychosocial concerns. These burdens vary with the economic and political situation of the different countries and are affected by such factors as an absence of screening programmes, insufficient cancer diagnostic and treatment services (especially in sparsely populated and rural areas), legal restrictions on access to drugs to relieve pain, and a medical culture in which quality-of-life considerations are undervalued in relation to imperatives to treat. These issues could be ameliorated by increased investment in cancer screening, removal of restrictions on prescription of opioids, and improvements in medical education to increase recognition of treatment futility. Supportive, palliative, and end-of-life care offer the potential to enhance quality of life, improve pain control, and reduce suffering for patients with cancer and their families, and to give patients a dignified death. All patients should have access to such care-in resource-rich regions these services should be integrated into oncology services, whereas in resource-poor regions they should be the main focus of treatment. The form of care should depend on the economic circumstances within and across countries, and recommendations are made across four resource classifications (basic to maximal) to take account of the diversity of settings in Asia.

摘要

亚洲的癌症负担沉重;2008 年亚洲大陆诊断出 610 万例新病例,占全球新发病例的 48%。由于人口老龄化和可改变的风险因素(如烟草和酒精使用、饮食和肥胖),癌症死亡人数预计将继续上升。大多数在亚洲被诊断患有癌症的患者疾病已处于晚期,无法进行治愈性治疗,这意味着他们可能会有疼痛和其他症状以及心理社会问题。这些负担因不同国家的经济和政治情况而异,并受到缺乏筛查计划、癌症诊断和治疗服务不足(特别是在人口稀少和农村地区)、法律限制获取缓解疼痛的药物以及医疗文化中对生活质量的重视不足等因素的影响,相对于治疗的必要性而言。通过增加癌症筛查的投资、取消阿片类药物处方的限制以及改善医学教育以提高对治疗无效性的认识,这些问题可以得到改善。姑息治疗和临终关怀有可能提高癌症患者及其家属的生活质量,改善疼痛控制,减轻他们的痛苦,并为患者提供有尊严的死亡。所有患者都应获得此类护理——在资源丰富的地区,这些服务应纳入肿瘤学服务,而在资源匮乏的地区,这些服务应成为治疗的主要重点。护理形式应取决于国家内部和国家之间的经济情况,并根据资源分类(从基本到最高)提出建议,以考虑亚洲各种环境的多样性。

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