Mangenot M, Chaize J, Haase M, Desfontaine M, Duvallet G, Moreau J P
Med Trop (Mars). 1979 Sep-Oct;39(5):531-5.
Can the diagnosis of sleeping sickness in patients immunologically suspect, without seeing the parasite, be obtained by dosing IgG and IgM? The authors demonstrate that two groups of people with positive immunodiagnosis, one parasitologically confirmed and the other not confirmed, do not show significant difference when dosing immunoglobulins. These two groups respectively show a significant difference when compared with a parasitologically and immunologicaly negative group. The simultaneous increase in IgG and IgM might confirm the immunodiagnosis.
对于免疫方面疑似患有昏睡病但未见到寄生虫的患者,能否通过检测IgG和IgM来做出诊断?作者证明,两组免疫诊断呈阳性的人群,一组经寄生虫学确诊,另一组未确诊,在检测免疫球蛋白时未显示出显著差异。与寄生虫学和免疫学均呈阴性的组相比,这两组分别显示出显著差异。IgG和IgM同时升高可能会证实免疫诊断。