Ratovitski E A, Shaposhnikov J D, Gaber V K, Knyazev P G
Neoplasma. 1979;26(3):251-60.
Proviral DNA from non-producer Rous sarcoma in Syrian hamster contains practically all the nucleotide sequences presented in 125I-labeled RNA from Rous sarcoma virus, Carr-Zilber strain. Virus-specific sequences consist of moderately reiterated and unique DNA regions. The amount of Rous sarcoma virus-specific provirus equivalents in hamster Rous sarcoma DNA is equal to 5.2 +/- 0.01. Experiments on transfection show that proviral DNA studied possesses biological activity in respect to cell transformation and virus production. The infectivity of DNA from hamster tumor does not depend on the expression of group-specific (gs) antigen in the recipient cells.
叙利亚仓鼠中非产生型劳氏肉瘤的前病毒DNA几乎包含了劳氏肉瘤病毒卡尔-齐尔伯株125I标记RNA中呈现的所有核苷酸序列。病毒特异性序列由中度重复和独特的DNA区域组成。仓鼠劳氏肉瘤DNA中劳氏肉瘤病毒特异性前病毒当量的数量等于5.2±0.01。转染实验表明，所研究的前病毒DNA在细胞转化和病毒产生方面具有生物活性。仓鼠肿瘤DNA的感染性不依赖于受体细胞中群特异性（gs）抗原的表达。
