仓鼠实验性隐孢子虫病
Experimental cryptosporidiosis in hamsters.
作者信息
Rossi P, Pozio E, Besse M G, Gomez Morales M A, La Rosa G
机构信息
Laboratory of Parasitology, Istituto Superiore di Sanità, Rome, Italy.
出版信息
J Clin Microbiol. 1990 Feb;28(2):356-7. doi: 10.1128/jcm.28.2.356-357.1990.
Abstract
A new laboratory animal model for experimental cryptosporidiosis is described. Adult immunosuppressed hamsters were infected per os with 0.5 x 10(5) and 1 x 10(5) Cryptosporidium oocysts of calf origin. The mean numbers of oocysts shed per gram of feces per day and the patterns of infection are described. The susceptibility to Cryptosporidium infection, the total number of oocysts shed (a thousand times the infective dose), and the ease of handling in laboratory conditions make hamsters a good animal model for cryptosporidiosis.
摘要
本文描述了一种用于实验性隐孢子虫病的新的实验动物模型。成年免疫抑制仓鼠经口感染了0.5×10⁵和1×10⁵个来源于小牛的隐孢子虫卵囊。描述了每天每克粪便中排出的卵囊平均数量以及感染模式。仓鼠对隐孢子虫感染的易感性、排出的卵囊总数（感染剂量的一千倍）以及在实验室条件下易于操作，使其成为隐孢子虫病的良好动物模型。
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